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Evaluation of dnDSA risk stratification using the updated PIRCHE-T2 model in two kidney transplant cohorts

Abstract: Development of de novo donor-specific antibodies (dnDSA) remains a key risk factor for antibody-mediated rejection and graft loss in kidney transplantation. The…

Date: 2026-04-20

Cytokine imbalance and immune network endotypes underlying heterogeneous response to omalizumab in chronic spontaneous urticaria

Abstract: Chronic spontaneous urticaria (CSU) exhibits marked immunologic heterogeneity, and a substantial proportion of patients show delayed or absent responses to anti-IgE…

Date: 2026-04-20

Non-invasive respiratory support attenuates lung damage in a murine model of bronchopulmonary dysplasia

Abstract: Bronchopulmonary dysplasia (BPD) is a chronic lung disease primarily affecting preterm infants exposed to prolonged oxygen therapy and mechanical ventilation. This study…

Date: 2026-04-20

Evaluation of unipolar and bipolar nanosecond pulses for calcium electrochemotherapy and immune response

Abstract: Calcium electrochemotherapy (CaECT) is an effective alternative to standard chemotherapeutic treatments, utilizing intracellular delivery of supraphysiological calcium…

Date: 2026-04-20

Limited immune perturbations in mice exposed to sustained low-dose ionizing radiation

Abstract: The effects of high-dose ionizing radiation (HDIR) exposure on the immune system are largely understood with consensus, yet there remains a fragmented understanding of…

Date: 2026-04-20

Cold-spot driven local failure after stereotactic body radiation therapy for colorectal liver metastases

Abstract: This single-institution retrospective study investigated whether actual dosimetric plan quality metrics better predict freedom from local progression (FFLP) than nominal…

Date: 2026-04-17

Analysis of mortality risk and influencing factors in female patients with young-onset type 2 diabetes

Abstract: To explore all-cause mortality risk and its influencing factors in female patients with young-onset type 2 diabetes mellitus (YOD). This cohort study included 5,984…

Date: 2026-04-17

Serum 25(OH)D3 level is associated with cognitive impairment in middle-aged and elderly patients with type 2 diabetes mellitus

Abstract: This study aimed to investigate the association between serum 25-hydroxyvitamin D3 (25(OH)D3) levels and cognitive impairment (CI) in middle-aged and elderly individuals…

Date: 2026-04-17

Multidimensional assessment of acne vulgaris: links between psychiatric symptoms, disordered eating, and dermatologic severity

Abstract: Acne vulgaris is a common chronic inflammatory skin disease that extends beyond dermatologic symptoms to include psychosocial and behavioral consequences. Although the…

Date: 2026-04-17

The impact of COVID-19 infection on the live birth rate in fresh embryo transfer cycles

Abstract: It is important to clarify the impact of COVID-19 on ART outcomes and to develop evidence-based guidelines for deciding whether to proceed with or cancel in vitro…

Date: 2026-04-17