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Neurological and hematological safety profiles of GSK-3? inhibitors: insights from multi-database pharmacovigilance and experimental validation

Abstract: Glycogen synthase kinase 3 beta (GSK-3?) inhibitors have received substantial attention for their therapeutic potential; however, their systemic safety profile remains…

Date: 2026-09-17

Clinical characteristics, management, and outcomes of lacrimal gland adenoid cystic carcinoma: a single-center series with contextual comparison to SEER data

Abstract: Lacrimal gland adenoid cystic carcinoma (LGACC) is a rare, aggressive malignancy with limited epidemiological data, particularly from East Asian populations. This…

Date: 2026-09-17

Integrating iHEC into standardized residency training for chronic disease management: a structural equation analysis of competency outcomes via digital health platforms

Abstract: To evaluate the association between an Intelligent Hypertension Excellence Centers (iHEC)-integrated teaching model and multidimensional educational outcomes in…

Date: 2026-09-17

Delta-9-tetrahydrocannabinol alleviates inflammation by modulating immune responses in LPS-induced murine inflammation model

Abstract: ? 9 -Tetrahydrocannabinol (THC), the primary psychoactive component of cannabis, has been reported to modulate immune responses; however, its effects on complex innate…

Date: 2026-09-16

Survival after hematopoietic cell transplantation in children and adults in four decades of experience: nationwide study

Abstract: The objective of this study was to provide a comprehensive nationwide analysis of the development of hematopoietic cell transplantation (HCT) in Poland in the years…

Date: 2026-09-16

Mind, body, health: qualitative insights into a holistic health concept for preschoolers

Abstract: The German holistic health Kneipp concept (KC) consists of five elements: water applications, physical activity, healthy nutrition, herbs, and mind–body practices.…

Date: 2026-09-16

Scrub typhus triggers hemophagocytic lymphohistiocytosis in children: metagenomic next-generation sequencing enables rapid diagnosis

Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome. Rapid identification of the underlying trigger is critical for effective…

Date: 2026-09-16

Association of obesity–metabolic phenotypes with coronary artery disease prevalence: interaction and exploratory mediation analyses of high-sensitivity C-reactive protein

Abstract: To investigate the associations of obesity–metabolic phenotypes with coronary artery disease (CAD) prevalence and to evaluate the interaction between obesity and…

Date: 2026-09-16

Body roundness index and adolescent metabolic syndrome: dose–response analysis and serum biomarker mediation

Abstract: The Body Roundness Index (BRI) combines waist circumference and height into a single geometric measure that is intended to reflect visceral adiposity. Its ability to…

Date: 2026-09-16

A fever-based therapeutic window for bronchoscopy to prevent bronchiolitis obliterans in children with Mycoplasma pneumoniae pneumonia

Abstract: Flexible bronchoscopy is frequently used in children with severe or refractory Mycoplasma pneumoniae pneumonia (MPP), but the optimal timing of intervention remains…

Date: 2026-09-16