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Real-world response rates in patients with human epidermal growth factor receptor 2-positive breast cancer after neoadjuvant treatment using dual human epidermal growth factor receptor 2 blockade

Abstract: Breast cancer (BC) is the most commonly diagnosed malignancy among women globally and in India. The human epidermal growth factor receptor 2 (HER2)-positive subtype is…

Date: 2026-09-09

Effects of acceptance and commitment therapy on fear of progression in young and middle-aged patients with breast cancer receiving particle therapy: a randomized controlled trial

Abstract: Young and middle-aged patients with breast cancer receiving particle therapy commonly experience elevated Fear of Progression (FoP). Evidence for the effectiveness of…

Date: 2026-09-09

Comparative predictive performance of different eGFR equations for 1-year major adverse cardiovascular events after percutaneous coronary intervention in patients with acute coronary syndrome

Abstract: Renal dysfunction is an important determinant of cardiovascular prognosis in patients with coronary artery disease. Estimated glomerular filtration rate (eGFR) is widely…

Date: 2026-09-09

First-day lactate trajectories and subsequent in-hospital mortality in cardiogenic shock: a landmark multicohort study

Abstract: Lactate in cardiogenic shock is commonly summarized by a single measurement or a two-point estimate of clearance, although its first-day pattern may offer a more…

Date: 2026-09-09

Pharmacological management and outcomes of sustained ventricular tachycardia in children and adolescents: a single-center retrospective study

Abstract: Evidence related to the efficacy and prognosis of pharmacologic therapy for sustained ventricular tachycardia (VT) in the pediatric population remains scarce. This…

Date: 2026-09-09

Identifying barriers to lipoprotein(a) testing in secondary cardiovascular prevention and co-designing implementation strategies: an Italian behavior change wheel-informed study

Abstract: Lipoprotein(a) [Lp(a)] is a causal risk factor for atherosclerotic cardiovascular disease, which remains unaddressed by current lipid-lowering therapies. Given its…

Date: 2026-09-09

C-reactive protein–triglyceride–glucose index and diabetes status for risk stratification in stage 4 cardiovascular–kidney–metabolic syndrome with acute decompensated heart failure: a retrospective cohort study

Abstract: Cardiovascular–kidney–metabolic (CKM) syndrome integrates metabolic dysfunction, kidney disease, and cardiovascular disease. In stage 4 CKM syndrome with acute…

Date: 2026-09-09

Paeoniflorin prevents acute graft-versus-host disease while preserving graft-versus-tumor effects

Abstract: Acute graft-versus-host disease (aGVHD) remains a major complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). This study investigated the…

Date: 2026-09-08

Hematologic response assessment in monoclonal gammopathy of renal significance: critical appraisal of current criteria

Abstract: Current recommendations for hematologic response (HemR) assessment in monoclonal gammopathies of renal significance (MGRS) are based on the monoclonal immunoglobulin…

Date: 2026-09-08

Increased interleukin-8 levels in cord blood serum of newborn—possible effect of cytokine dysregulation in pregnancies complicated by rheumatic disease on newborn vasculature

Abstract: Systemic autoimmune rheumatic diseases (SARDs) are associated with a higher risk of cardiovascular diseases. During pregnancy, maternal immune disbalance might impact…

Date: 2026-09-08