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Serum endocan levels in patients with peripheral artery disease: an exploratory cross-sectional study

Abstract: To explore whether circulating endocan concentrations differ between adults with imaging-confirmed peripheral artery disease (PAD) and controls without clinically…

Date: 2026-08-06

Prolonged SARS-CoV-2 infection in hematologic malignancies: clinical impact, risk factors and intra-host viral evolution

Abstract: Prolonged SARS-CoV-2 infection in hematologic patients may go unrecognized. The aim of the study is to describe the incidence, risk factors, viral evolution and clinical…

Date: 2026-08-05

Prognostic and biological significance of MRPL13 in multiple myeloma: evidence from multi-cohort, single-cell analyses

Abstract: Multiple myeloma (MM) is a clonal plasma cell malignancy with high heterogeneity and poor prognosis. Mitochondrial ribosomal protein L13 (MRPL13) has been linked to…

Date: 2026-08-05

Association between islet ?-cell function and time in range in patients with type 2 diabetes mellitus: a retrospective cross-sectional study

Abstract: Impaired islet ? -cell function is the core mechanism underlying type 2 diabetes mellitus (T2DM). This study investigated the association between islet ? -cell function…

Date: 2026-08-05

Triglyceride–glucose index and hyperhomocysteinemia within a cardiovascular–kidney–metabolic biomarker network: insights from interpretable machine learning and epidemiological modeling

Abstract: Although the triglyceride–glucose (TyG) index is an established surrogate marker of insulin resistance and metabolic burden, its relationship with hyperhomocysteinemia…

Date: 2026-08-05

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and sarcopenia with mediating role of triglyceride glucose-related indices: a cohort study in Chinese elderly adults

Abstract: The present study aims to investigate the association and dose-response relationship between the non-high-density lipoprotein cholesterol to high-density lipoprotein…

Date: 2026-08-05

Construction and validation of a risk prediction model for vitamin D deficiency in patients with type 2 diabetes mellitus

Abstract: Patients with type 2 diabetes mellitus (T2DM) have a high prevalence of vitamin D deficiency, but convenient and efficient screening tools are lacking in clinical…

Date: 2026-08-05

Adverse cardio-metabolic risk profile and epicardial adiposity in patients with adrenal adenoma: a cross-sectional study

Abstract: Mild autonomous cortisol secretion (MACS) is associated with an increased cardiovascular mortality, but even patients with non-functioning adrenal adenoma (NFA) might be…

Date: 2026-08-05

Association between pregnancy cumulative glycemic exposure and postpartum glucose metabolism outcomes at 4–7?years: a cohort study

Abstract: This study aimed to investigate the association between cumulative glycemic exposure (CGE) during pregnancy and glycemic metabolism abnormality (GMA) at 4–7?years…

Date: 2026-08-05

Contribution of monocyte subpopulations to the pathogenesis and therapy outcome of type 1 diabetes management in pediatric patients

Abstract: Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by the destruction of pancreas ? cells causing impairment in insulin secretion. Despite various…

Date: 2026-08-05