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Heart 3D: echocardiographic and anatomical features of the tricuspid valve in a heterogeneous population with severe regurgitation—implications for edge-to-edge procedure suitability

Abstract: To assess the incremental value of real-time three-dimensional (3D) transesophageal echocardiography (TEE) in visualizing tricuspid valve (TV) anatomy for procedural…

Date: 2025-08-22

Real-world experience with the use of diazoxide among people living with congenital hyperinsulinism and their caregivers

Abstract: Congenital hyperinsulinism (HI) is a rare disease that causes severe hypoglycemia. Diazoxide is the first-line treatment; however, many individuals using diazoxide…

Date: 2025-08-21

Chitosan nanoparticles-encapsulated cannabis extracts and their antimicrobial potential against skin pathogens

Abstract: Cannabis compounds are well-known for their therapeutic applications in the treatment of various health issues. These substances, mainly cannabinoids, are known for…

Date: 2025-08-21

Attenuation of IFITM proteins’ antiviral activity through sequestration into intraluminal vesicles of late endosomes

Abstract: Interferon-induced transmembrane proteins (IFITMs) inhibit the entry of diverse enveloped viruses. The spectrum of antiviral activity of IFITMs is largely determined by…

Date: 2025-08-21

Impact of catheter-to-vein diameter ratio on thrombosis in pediatric central venous catheterization

Abstract: Catheter-related thrombosis is a common complication of central venous catheter insertion. As the use of central venous catheters increases in pediatric critical care…

Date: 2025-08-21

Low-dose extracorporeal shock wave attenuates sepsis-related acute lung injury by targeting mitochondrial dysfunction and pyroptosis crosstalk in type II alveolar epithelial cells

Abstract: The pathological mechanism of sepsis-related acute lung injury (ALI) is closely linked to mitochondrial dysfunction and pyroptosis. Although low-dose extracorporeal…

Date: 2025-08-21

Mugwort sensitization and asthma as predictors of food-induced anaphylactic shock in children: a retrospective study in Northern China

Abstract: Food-induced anaphylactic shock is the most severe and life-threatening manifestation of food allergy in children. However, its underlying risk factors remain poorly…

Date: 2025-08-21

The effect of modulators on lung function following inpatient treatment for CF exacerbations

Abstract: Modulator therapy restores CFTR function and has led to health benefits for persons with cystic fibrosis (CF) (PwCF), including lower rates of pulmonary exacerbations.…

Date: 2025-08-21

Development and validation of a nomogram model for sleep disorders in patients with recurrent implantation failure based on physiological and lifestyle factors

Abstract: To establish and validate a nomogram model for the quality of sleep in patients with recurrent implantation failure (RIF) and to evaluate its performance. From January…

Date: 2025-08-21

Potential role of 4-hydroxyisoleucine in enhancing fertility in male mice with diet-induced obesity

Abstract: Obesity is associated with hormonal imbalance, increased oxidative stress, and inflammation in the testis. These conditions adversely affect sperm quality, leading to…

Date: 2025-08-21