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Cerebellar ataxia-onset ALS with SOD1 D91A mutation: a rare phenotype

Abstract: Amyotrophic lateral sclerosis (ALS) associated with mutations in the superoxide dismutase 1 ( SOD1 ) gene is recognized for phenotypic variability, yet cerebellar ataxia…

Date: 2026-08-04

Admission systemic inflammatory indices and 6-month functional outcome after endovascular thrombectomy for acute ischemic stroke: an exploratory single-center cohort study

Abstract: Many patients still have poor functional outcomes after endovascular thrombectomy (EVT) for acute ischemic stroke. Systemic inflammatory indices from routine blood tests…

Date: 2026-08-04

Treatment of anti-GAD65 antibody-positive epilepsy and cerebellar ataxia with efgartigimod: a case report and literature review

Abstract: Anti-glutamic acid decarboxylase 65 (GAD65) antibody-associated neurological syndrome is a rare autoimmune disorder with heterogeneous clinical manifestations, including…

Date: 2026-08-04

Defining nature, responses and drivers of regulatory- and conventional CD4 + T cells in the human term decidua

Abstract: During mammalian pregnancy, a maternal immunoregulatory network develops in the decidua that fosters fetal development, maintains tolerance to fetal antigens and…

Date: 2026-08-04

Metastatic organ distribution characteristics and prognosis in patients with non-small cell lung cancer

Abstract: Non-small cell lung cancer (NSCLC) is often diagnosed at advanced stages, with distant metastasis being the leading cause of death. However, the distribution patterns of…

Date: 2026-08-04

Enhancing multimodal survival prediction: tri-modal learning with clinical knowledge integration via state space models

Abstract: Accurate survival prediction is crucial for precision oncology, yet it faces challenges due to the neglect of clinical priors and high computational complexity. We…

Date: 2026-08-04

Coordinated dynamics of circulating neutrophils, regulatory T lymphocytes, myeloid derived suppressor cells and distinct granulocytic subsets reveal a complex immune network in metastatic colorectal cancer

Abstract: Circulating immune cells serve as readily accessible biomarkers in cancer patients. Some of them, such as neutrophils, lymphocytes as well as the neutrophil to…

Date: 2026-08-04

Deep learning models based on CT predict prognosis in patients with locally advanced esophageal squamous cell carcinoma who received neoadjuvant immunotherapy and chemotherapy

Abstract: Neoadjuvant immunotherapy and chemotherapy (NICT) has emerged as the standard pharmacological intervention for locally advanced esophageal squamous cell carcinoma…

Date: 2026-08-04

Predictors of survival in triple-negative breast cancer patients treated with neoadjuvant chemotherapy, surgery, and radiotherapy

Abstract: Triple-negative breast cancer (TNBC) is known for its heterogeneity. Due to the small sample sizes in prior studies, there is limited understanding of whether different…

Date: 2026-08-04

Electric field effects of pulsed field ablation through adjacent non-cardiac tissues in an in vitro hybrid model

Abstract: Endocardial ablation of atrial arrhythmias may occasionally produce insufficient lesion depth. Pulsed-field ablation (PFA) may generate measurable electroporation…

Date: 2026-08-04