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Ultrathin-strut drug-eluting stents are associated with lower revascularization rates than drug-coated balloons in non-focal in-stent restenosis

Abstract: In-stent restenosis (ISR) remains a significant clinical challenge despite advances in drug-eluting stent (DES) technology. Although current guidelines recommend…

Date: 2026-08-03

Analysis of the efficacy of transesophageal atrial pacing in the treatment of supraventricular tachycardia in newborns

Abstract: To describe and explore the therapeutic value of transesophageal atrial pacing (TEAP) for supraventricular tachycardia in newborns. Clinical data from 22 cases (15…

Date: 2026-08-03

Correlation between the CD8 + T cell/IFN- ? axis and clinical disease progression at different phases of ITP

Abstract: Primary immune thrombocytopenia (ITP) represents the most common acquired bleeding disorder among children. Since its immune mechanism is not fully clarified, precise…

Date: 2026-07-31

Blood viscosity as a continuous marker of cardio-metabolic risk burden: a large-scale cross-sectional study of 38,574 adults

Abstract: Metabolic syndrome (MetS) is diagnosed using fixed thresholds that may not fully reflect the continuous accumulation of cardio-metabolic risk. We investigated whether…

Date: 2026-07-31

Acceleration of type 1 diabetes onset during the COVID-19 pandemic

Abstract: Studies since the beginning of the COVID-19 pandemic suggest an increase in new cases of type 1 diabetes (T1D) but the etiology of this increase remains unclear. To…

Date: 2026-07-31

AMPK-OXSR1 signaling coordinates proximal tubular sodium transport and is modulated by canagliflozin

Abstract: The with-no-lysine kinase (WNK)/oxidative stress-responsive kinase 1 (OXSR1) pathway is vital for renal sodium transport in the distal nephrons as it regulates chloride…

Date: 2026-07-31

Thyroid hormone sensitivity, insulin resistance and visceral fat area as determinants of prevalent coronary heart disease in euthyroid patients with type 2 diabetes

Abstract: Coronary heart disease (CHD) remains a leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Whether thyroid hormone sensitivity…

Date: 2026-07-31

Association of hepatic steatosis with MRI-defined renal steatosis in type 2 diabetes: a cross-sectional imaging and clinical modeling study

Abstract: Fatty Kidney Disease (FKD) is increasingly recognized as a distinct clinical entity, often coexisting with metabolic dysfunction-associated fatty liver disease (MAFLD)…

Date: 2026-07-31

Qing-Re-Qu-Shi formula improves clinical outcomes and is accompanied by gut microbiota and microbial metabolite remodeling in adults with moderate atopic dermatitis: a randomized placebo-controlled multi-omics trial

Abstract: The gut–skin axis is increasingly implicated in atopic dermatitis (AD), but randomized adult studies linking clinical response to paired gut microbiome and circulating…

Date: 2026-07-31

Trajectory-based profiling of 52-week secukinumab response reveals baseline clinical and transcriptomic differences in plaque psoriasis

Abstract: Response to secukinumab in psoriasis varies over time and is not fully captured by single timepoint endpoints. Baseline features associated with long-term response…

Date: 2026-07-31