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Development and validation of a nomogram model for prediction of dyslipidemia in children with Wilson disease: a retrospective analysis

Abstract: Wilson disease (WD), an inherited copper metabolism disorder, is linked to hepatic injury from copper accumulation-induced dyslipidemia. Children with WD have a high…

Date: 2025-08-21

Analysis of influencing factors and interaction effects on stroke recurrence in patients with middle cerebral artery occlusion treated with mechanical thrombectomy

Abstract: Stroke recurrence is an important factor affecting the prognosis of mechanical thrombectomy in patients with middle cerebral artery (MCA) occlusion. This study aims to…

Date: 2025-08-21

Prognostic significance of FT3 levels in hypertrophic cardiomyopathy patients with HFpEF

Abstract: This study sought to identify key prognostic factors in patients with hypertrophic cardiomyopathy (HCM) and heart failure with preserved ejection fraction (HFpEF),…

Date: 2025-08-21

Relationship between inflammatory markers and long-term prognosis in ICU patients with acute non-ST-segment elevation myocardial infarction

Abstract: This study aims to investigate the relation of inflammatory markers to the long-term prognosis of patients with severe non-ST-segment elevation myocardial infarction…

Date: 2025-08-21

Genotype clinical phenotype analysis of 35 cases of hereditary spherocytosis in children

Abstract: Hereditary spherocytosis (HS) is a common red blood cell membrane disease. It is currently clear that mutations in genes such as ANK1, SPTB, SPTA1, SLC4A1, EPB4.2 can…

Date: 2025-08-20

PD-L1 + neutrophils mediate immune regulation of CD8 + T cells in halo nevi

Abstract: Halo nevi are clinically common and are characterized by a circle of leukoderma around the central melanocytic nevus. Studies have shown that the pathogenesis of halo…

Date: 2025-08-20

Tofacitinib as an adjuvant treatment for pediatric Still's disease

Abstract: To describe the efficacy and safety of tofacitinib for pediatric Still's disease, also referred to as systemic-onset juvenile idiopathic arthritis (sJIA). Traditional…

Date: 2025-08-20

Parents’ understanding and attitudes toward the application of AI in pediatric healthcare: a cross-sectional survey study

Abstract: To investigate parents’ understanding and attitudes toward the application of Artificial Intelligence (AI) in pediatric healthcare. An observational, cross-sectional…

Date: 2025-08-20

Neurodevelopmental impact of early diagnostic imaging in preterm infants: quantifying risk and the role of point-of-care ultrasound

Abstract: Medical imaging is essential in neonatal intensive care units (NICUs), particularly for the management of preterm infants. However, concerns persist regarding the…

Date: 2025-08-20

Genetic etiology and pregnancy outcomes of fetal hyperechoic kidneys: a retrospective analysis

Abstract: Fetal hyperechoic kidney is an important soft marker in prenatal ultrasonography; however, the causes of this phenomenon are unclear. Therefore, we analyzed genetic…

Date: 2025-08-20