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Construction and validation of a sepsis prediction model using inflammatory and hemodynamic markers in the emergency department

Abstract: To develop an early diagnosis prediction model for sepsis in the emergency department by integrating inflammatory, hemodynamic, and nursing assessment indicators. A…

Date: 2026-07-29

Xuebijing alleviates acute hydrogen sulfide-induced pyroptosis in rat spleen via suppression of the caspase-1/NLRP3 pathway

Abstract: Hydrogen sulfide (H 2 S) is a pervasive environmental toxicant with well-established immunotoxic effects. However, its action on lymphoid organs—particularly whether it…

Date: 2026-07-29

Development and external validation of a machine learning model for predicting 28-day mortality in patients with acute myocardial infarction complicated by malignant arrhythmia: a study using the MIMIC database and a Chinese cohort

Abstract: Acute myocardial infarction (AMI) complicated by malignant ventricular arrhythmia (MVA) carries high 28-day mortality. Existing risk scores inadequately capture this…

Date: 2026-07-29

Serum lipidomic alterations associated with post-stroke cognitive impairment: an exploratory prospective study

Abstract: Post-stroke cognitive impairment (PSCI) is a common complication of stroke that adversely affects long-term functional outcomes and quality of life among survivors.…

Date: 2026-07-29

Predictive value of systemic inflammatory response index for coronary artery disease and angiographic severity: a single-center retrospective study

Abstract: Systemic inflammation plays a pivotal role in coronary artery disease (CAD). Systemic inflammatory response index (SIRI), a composite biomarker derived from neutrophil,…

Date: 2026-07-29

Risk factors analysis and risk prediction model establishment for heterotopic ossification after open reduction and internal fixation of distal humeral fractures: a retrospective cohort study

Abstract: To identify independent risk factors for heterotopic ossification (HO) after open reduction and internal fixation (ORIF) of distal humeral fractures, and to construct…

Date: 2026-07-29

Perceptions of dogs and animal-assisted support programs among veterinary students and teaching staff in Romania

Abstract: Animal-assisted support programs (AASP) are increasingly used to promote psychological wellbeing in educational settings, yet their acceptability within veterinary…

Date: 2026-07-29

Cross-cultural adaptation and psychometric validation of the Chinese version of the empathy fatigue scale for health professionals among intensive care unit nurses

Abstract: Intensive care unit (ICU) nurses are chronically exposed to patient suffering, death, and morally complex decisions, placing them at elevated risk of empathy fatigue.…

Date: 2026-07-29

Incremental predictive value of a CT-based deep learning radiomics model for differentiating benign and malignant pleural effusions

Abstract: To develop and validate a diagnostic model for malignant (MPE) and benign pleural effusion (BPE) using non-contrast chest CT deep learning (DL) and radiomics features,…

Date: 2026-07-29

Genetics and epigenetics in tumor necrosis factor-alpha ( TNF-? ) and transmembrane 6 superfamily member 2 ( TM6SF2 ) in alcohol induced liver cirrhosis

Abstract: Alcohol dependence and cirrhosis are key outcomes of increased alcohol use, with genetic factors increasingly implicated. A functional promoter variant (rs361525) in the…

Date: 2026-07-29