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An interpretable machine learning approach for predicting drug-resistant epilepsy in children with tuberous sclerosis complex

Abstract: This study developed and validated an interpretable machine learning (ML) algorithm for predicting the risk of drug-resistant epilepsy (DRE) in children with Tuberous…

Date: 2025-08-04

A study on the distribution of interleukin-10 gene polymorphisms and their association with febrile seizure susceptibility in children from the Wenzhou region, Zhejiang Province

Abstract: Febrile seizures (FS) were the most common seizure disorder in young children, with a notable prevalence in the Zhejiang Province region of China. The pathogenesis of FS…

Date: 2025-08-04

The diagnostic value of lymphocyte profiling for infectious mononucleosis and mycoplasma pneumoniae pneumonia

Abstract: Infectious mononucleosis (IM) and mycoplasma pneumoniae pneumonia (MPP) are common pediatric diseases that can easily trigger immune responses. This study aims to detect…

Date: 2025-08-01

Case report of non-gene editing CD7 CAR T cell therapy in CD7 + Sézary syndrome: preclinical validation and first-in-human use

Abstract: Sézary syndrome (SS) is a leukemic form of cutaneous T cell lymphoma (CTCL), distinguished from mycosis fungoides by the presence of cancerous lymphocytes in the blood…

Date: 2025-08-01

Correlation study on the risk of cardiovascular adverse events in diabetic foot patients based on machine learning - a retrospective cohort study

Abstract: Diabetic Foot (DF), as a serious complication of diabetes, is closely related to major adverse cardiovascular events (MACE) and mortality. However, research on…

Date: 2025-08-01

Effects of high-dose vitamin D supplementation on bone mineral density in very low birth weight preterm infants

Abstract: Vitamin D deficiency is common among very low birth weight (VLBW) preterm infants due to challenges in achieving adequate enteral nutrition and reduced transplacental…

Date: 2025-08-01

The critical role of diet, exercise, and sleep in shaping the gut microbiota of children with idiopathic short stature: a Retrospective study

Abstract: To investigate the gut microbiota in children with varying degrees of idiopathic short stature (ISS) and to examine the relationship between their intestinal microbiota…

Date: 2025-08-01

Patient demographics, clinical characteristics and genetic mutations of DMD and BMD patients in Qatar Epidemiological and genetic profile of Duchenne muscular dystrophy and Becker muscular dystrophy patients in Qatar: a retrospective cohort study

Abstract: Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are rare X-linked neuromuscular disorders that typically begin in childhood and progress to…

Date: 2025-08-01

Influence of oropharyngeal therapy with mother’s own milk on the microbiome and metabolome of very preterm infants: a pilot study

Abstract: Oropharyngeal therapy with mother’s own milk (OPT-MOM) may serve as a promising therapeutic approach to elicit immunoprotective and anti-inflammatory benefits for…

Date: 2025-08-01

Single-agent rituximab and ultra-low-dose adaptive radiotherapy for the treatment of indolent B-cell non-Hodgkin lymphomas

Abstract: For indolent B-cell non-Hodgkin lymphomas (iNHLs), ultra-low-dose radiation therapy (ULDRT) with 4 Gy has demonstrated durable local control (70%), although distal…

Date: 2025-07-31