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Risk factors associated with renal injury in patients initially diagnosed with IgA vasculitis

Abstract: To explore the risk factors associated with renal injury in patients diagnosed with IgA vasculitis at initial presentation. A retrospective analysis was conducted on the…

Date: 2025-07-29

Nutritional and immune-inflammatory scoring system for predicting outcomes in newly diagnosed diffuse large B-cell lymphoma patients

Abstract: Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive non-Hodgkin lymphoma and often carries a poor prognosis. Current prognostic systems such as the…

Date: 2025-07-28

Global, regional, and national anemia burden among women of reproductive age (15–49 years) from 1990 to 2021: an analysis of the Global Burden of Disease Study 2021

Abstract: Anemia remains a significant global health challenge, disproportionately affecting women of reproductive age (WRA, 15 to 49 years) due to physiological and socioeconomic…

Date: 2025-07-28

Downregulated PTEN and aberrant JAK–STAT signal pathway in essential thrombocythemia patients

Abstract: Background: Essential thrombocythemia (ET) is one of the Philadelphia-negative (Ph?) classical myeloproliferative neoplasms (MPNs), characterized by increased…

Date: 2025-05-23

RET fusion driven (RETfus+) non-small cell lung cancer: a comprehensive genomic profiling study with histologic correlation

Abstract: Background: Fusion of the RET gene resulting in clinically significant Genomic Alteration (GA) occur in 1-2% of NSCLC in the United States and has emerged as a major…

Date: 2025-05-16

Dynamic ferritin levels and survival outcomes in secondary hemophagocytic syndrome: a comprehensive analysis

Abstract: Background: Hemophagocytic syndrome (HPS) is a life-threatening condition characterized by excessive immune activation and cytokine release. Reliable prognostic markers…

Date: 2025-05-15

Olverembatinib (HQP1351)-based therapy in adults with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia or chronic myeloid leukemia in blast phase: results from a real-world study

Abstract: Background: Relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (R/R Ph+ ALL) and chronic myeloid leukemia in the blast phase (CML-BP)…

Date: 2025-05-14

Mogamulizumab in combination improves clinical outcomes in relapsed and refractory Sézary syndrome

Abstract: Introduction: Sézary syndrome (SS) is an aggressive variant of cutaneous T-cell lymphoma (CTCL) that presents with generalized erythroderma, lymphadenopathy, peripheral…

Date: 2025-05-14

Efficacy and safety of pegylated interferon in the treatment of JAK2V617F-positive polycythemia vera with a dose de-escalation strategy: a single-center retrospective study

Abstract: Introduction: Although pegylated interferon (PEG-IFN) has been widely used in the treatment of polycythemia vera (PV), there is still a significant variability in its…

Date: 2025-05-14