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Implementation of a spaced-repetition approach to enhance undergraduate learning and engagement in paediatrics

Abstract: Knowledge retention is crucial in medical education, yet traditional study methods often fail to ensure long-term recall. Spaced repetition, a cognitive learning…

Date: 2025-07-30

Molecular subtypes, prognostic factors, and treatment optimization in pediatric medulloblastoma: a real-world study from China

Abstract: Medulloblastoma (MB) is the most common malignant pediatric brain tumor, yet systematic studies on molecular characteristics and treatment efficacy in Chinese pediatric…

Date: 2025-07-30

Pharmacokinetics of levosimendan in critically Ill children on extracorporeal membrane oxygenation: a prospective observational study

Abstract: Levosimendan is used off-label in pediatrics and pharmacokinetic (PK) data in this population are scarce. The only study in critically ill patients on extracorporeal…

Date: 2025-07-30

Study on the 1990–2021 trend of global childhood respiratory infection and tuberculosis disease burden and related risk factors

Abstract: Respiratory tract infections (RTIs) and tuberculosis (TB) impose a critical global health burden on children, serving as leading causes of morbidity and mortality. Lower…

Date: 2025-07-30

High prevalence but low referral rate of adrenal incidentalomas in a Lebanese tertiary hospital

Abstract: Adrenal incidentalomas (AI) are being more frequently reported with the advent of medical imaging. Studies on their prevalence, characteristics and functional status are…

Date: 2025-07-29

Global, regional, and national burden of Pediatric and adolescent thyroid cancer from 1990 to 2021: a statistical analysis of prevalence, incidence, and DALYs

Abstract: Thyroid cancer is the most common malignant tumor of the endocrine system. Among children and adolescents, cancer ranks as the fourth leading cause of cancer-related…

Date: 2025-07-29

Serum levels of interleukin-17, -18, -22, and -25 in patients with bullous pemphigoid before and after treatment

Abstract: This study aimed to explore the relationship between serum levels of interleukin-17 (IL-17), interleukin-18 (IL-18), interleukin-22 (IL-22), interleukin-25 (IL-25),…

Date: 2025-07-29

Burden of ageing spectrum of diseases in China, 1990–2021: a systematic analysis of global burden of disease study 2021

Abstract: Population aging represents a pressing challenge for China, given its vast population and the growing proportion of adults aged 65?years and older. The study aimed to…

Date: 2025-07-29

ROR?-activated mitophagy attenuating hypoxic-ischemic encephalopathy via suppression of microglial cGAS-STING axis

Abstract: Hypoxic-ischemic encephalopathy (HIE) involves neuroinflammation driven by microglial activation, yet regulatory mechanisms remain poorly defined. This study…

Date: 2025-07-29

Development and validation of a CD4+/CD8+ ratio-based nomogram to predict plastic bronchitis in pediatric Mycoplasma pneumoniae pneumonia

Abstract: Plastic bronchitis (PB) is a rare but severe complication of Mycoplasma pneumoniae pneumonia (MPP) in children. Early identification of PB is critical for timely…

Date: 2025-07-29