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Efficacy and safety of hydromorphone for postoperative patient-controlled intravenous analgesia for patients undergoing orthopedic surgery: a randomized, double-blinded controlled trial

Abstract: Background: The study aimed to evaluate the efficacy and safety of hydromorphone in postoperative patient-controlled intravenous analgesia (PCIA) for orthopedic surgery…

Date: 2025-04-28

Development and validation of a postoperative delirium risk prediction model for non-cardiac surgery in elderly patients

Abstract: Background: Postoperative delirium (POD) is one of the common central nervous system complications in elderly patients after non-cardiac surgery. Therefore, it is…

Date: 2025-04-28

Retrograde inferior vena cava perfusion reduces the risk of acute kidney injury depending on the oxygen extraction ratio. A retrospective cohort study

Abstract: Background: Total aortic arch replacement surgery (TARS) for Acute type A aortic dissection is associated with high incidence of postoperative acute kidney injury (AKI),…

Date: 2025-04-28

Exploring the association between dietary caffeine and chronic musculoskeletal pain: a cross-sectional analysis of NHANES

Abstract: Background: The association between dietary caffeine intake and chronic musculoskeletal pain (CMP) remains unclear, with previous studies yielding conflicting results.…

Date: 2025-04-28

Effect of dexmedetomidine on the median effective concentration of ropivacaine for postoperative analgesia in transversus abdominis plane block: an up-down sequential allocation study

Abstract: Background: This study aimed to observe the effect of dexmedetomidine on the median effective concentration (EC50) of ropivacaine for postoperative analgesia in…

Date: 2025-04-28

The dialogue dilemma: the role of patient-clinician communication for low-income people who smoke and manage multiple conditions

Abstract: Introduction: Adults from low-income backgrounds who smoke face significant health disparities related to tobacco use, often at disproportionately high rates. These…

Date: 2025-04-28

Reduced finger tapping speed in patients with schizophrenia and psychomotor slowing: an exploratory fMRI study

Abstract: Introduction: Motor symptoms are frequent in patients with schizophrenia and have multiple presentations, one of which is psychomotor slowing. Understanding the neural…

Date: 2025-04-28