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Lower pre-conditioning absolute lymphocyte counts are associated with worse outcomes in haploidentical stem cell transplantation with myeloablative regimen in children

Abstract: Background: Anti-thymocyte globulin (ATG) is frequently administered for preventing graft-versus-host disease (GVHD) in allogeneic hematopoietic stem cell…

Date: 2025-03-25

An interpreting machine learning models to predict amputation risk in patients with diabetic foot ulcers: a multi-center study

Abstract: Background: Diabetic foot ulcers (DFUs) constitute a significant complication among individuals with diabetes and serve as a primary cause of nontraumatic…

Date: 2025-03-25

Curcumin targets YAP1 to enhance mitochondrial function and autophagy, protecting against UVB-induced photodamage

Abstract: Background: Ultraviolet B (UVB) radiation is a major environmental factor contributing to skin damage via DNA damage, oxidative stress, inflammation, and collagen…

Date: 2025-03-25

Characterizing the immune infiltrate in secondary syphilis: implications for transmission and pathology

Abstract: Introduction: Syphilis is a complex disease with variable clinical presentation where symptomatic and potentially infectious stages alternate with periods of latency,…

Date: 2025-03-25

Performance of fasting plasma glucose for community-based screening of undiagnosed diabetes and pre-diabetes in sub-Saharan Africa

Abstract: Introduction: Early diabetes screening is critical in sub-Saharan Africa (SSA), where the prevalence is increasing, yet a large proportion of cases remain undiagnosed.…

Date: 2025-03-25

Unseen dualities: underdiagnosis of substance use disorders in borderline personality disorder

Abstract: Introduction: Borderline personality disorder (BPD) patients exhibit high rates of co-occurring mental disorders. Though literature reports varying prevalence of…

Date: 2025-03-25