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BMI-stratified nomograms to predict early SIRS-defined sepsis after flexible ureteroscopy

Abstract: Postoperative sepsis is a serious complication of flexible ureteroscopy (FURS). Body mass index (BMI) may modify risk, but BMI-stratified prediction models are lacking.…

Date: 2026-07-16

CACUL1 promotes hepatocellular carcinoma progression through enhanced tumor cell proliferation and macrophage-mediated immune suppression

Abstract: Although cullin-family E3 ubiquitin ligases regulate diverse oncogenic pathways, the role of CACUL1 in hepatocellular carcinoma (HCC) remains poorly characterized. We…

Date: 2026-07-16

The prognostic significance of immunohistochemical expressions of proliferating cell nuclear antigen, P16 and Ki-67 in breast cancer

Abstract: This study investigates the link between proliferation markers (PCNA, p16, Ki-67) and histopathological factors, exploring their prognostic value in breast cancer…

Date: 2026-07-16

Development and validation of a nomogram to predict symptomatic recurrence following laparoscopic adenomyomectomy

Abstract: Nomograms are intuitive graphical tools that integrate multiple prognostic variables to generate individualized risk estimates. To date, no study has developed a…

Date: 2026-07-16

Maternal health literacy status and associated factors among pregnant women: a cross-sectional study in Chongqing, China

Abstract: Maternal health literacy (MHL) plays a critical role in improving perinatal outcomes. This study aimed to investigate MHL status and its associated factors among…

Date: 2026-07-16

Surgical decision-making for primary stress urinary incontinence: insights from a nationwide survey of gynecologists in Turkey

Abstract: To delineate the surgical preferences of gynecologists in the management of primary stress urinary incontinence (SUI) and to explore the extent to which clinical…

Date: 2026-07-16

Prophylactic epidural blood patch for cerebrospinal fluid leakage after intrathecal drug delivery system implantation in patients with refractory cancer pain: a multi-center retrospective cohort study

Abstract: Current guidelines for postdural puncture cerebrospinal fluid (CSF) leakage advocate conservative management, extrapolated from general populations. Patients with…

Date: 2026-07-16

Elevated GDF15 in ocular fluids of patients with proliferative diabetic retinopathy

Abstract: Growth differentiation factor 15 (GDF15) is a multifunctional stress-responsive cytokine widely involved in inflammation, oxidative stress, and microvascular injury. Its…

Date: 2026-07-16

SGLT2 inhibitors and diabetic retinopathy progression: evidence from a retrospective cohort study and Mendelian randomization analysis

Abstract: To investigate the association between sodium-glucose cotransporter 2 inhibitors (SGLT2i) use and diabetic retinopathy (DR) progression, and to explore supporting…

Date: 2026-07-16

Analysis of the effectiveness of arthroscopic cannulated screw fixation for coracoid process fractures

Abstract: To evaluate the effectiveness of minimally invasive arthroscopic treatment for coracoid process fractures. This retrospective study analyzed 17 patients with coracoid…

Date: 2026-07-16