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Development and validation of a machine learning-based early warning model for bone metastasis in newly diagnosed prostate cancer

Abstract: Bone metastasis (BM) is common in newly diagnosed prostate cancer (PCa), particularly in patients with advanced disease at presentation. However, the indications for…

Date: 2026-07-09

Prediction model for early neurological deterioration in large artery atherosclerotic stroke

Abstract: To develop and validate a predictive model for early neurological deterioration (END) in acute ischemic stroke due to large artery atherosclerosis. We included 433…

Date: 2026-07-09

Precise discrimination of mycobacterial pulmonary diseases via multimodal machine learning integrating chest CT and clinical markers

Abstract: Differentiating Mycobacterium tuberculosis lung disease (MTB-LD) from nontuberculous mycobacterial lung disease (NTM-LD) remains clinically challenging because of…

Date: 2026-07-09

Assessing multiple-choice question quality in internal medicine: a comparative analysis of three large language models against expert consensus

Abstract: Large language models (LLMs) are increasingly explored for their potential to support quality assurance in medical education assessment. However, limited evidence exists…

Date: 2026-07-09

Evaluating objective nutritional biomarkers for the prediction of sarcopenia in Crohn’s disease: development and internal validation of a clinical nomogram

Abstract: Sarcopenia is prevalent in Crohn’s disease (CD) and correlates with adverse clinical outcomes; however, routine computed tomography (CT) screening is limited in daily…

Date: 2026-07-09

Integrative analysis of FAERS, network toxicology, and Mendelian randomization identifies potential targets in paclitaxel-associated systemic sclerosis

Abstract: Systemic sclerosis (SSc) is a rare and complex autoimmune disease characterized by fibrosis of the skin and internal organs as well as vascular abnormalities. Studies…

Date: 2026-07-09

Assessing the knowledge, attitudes and practices of physicians on perioperative antibiotic prophylaxis in pediatric surgery in China: a descriptive study

Abstract: Surgical site infection (SSI) prevention is a critical component of pediatric surgical safety, yet the irrational prolongation of perioperative antimicrobial prophylaxis…

Date: 2026-07-09

Association between nutritional literacy and cancer anorexia among gastrointestinal cancer patients: a moderated mediation analysis on the roles of self-efficacy and family support

Abstract: To test the relationship between nutritional literacy, self-efficacy, family support and cancer anorexic behavior among patients with gastrointestinal cancer undergoing…

Date: 2026-07-09

Prediction of depressive symptoms in middle-aged and older adult hospitalized patients with chronic diseases: a multicenter study in Anhui, China using machine learning methods

Abstract: This cross-sectional study has dual objectives: to investigate the predictive value of machine learning (ML) for the prevalence of depressive symptoms in middle-aged and…

Date: 2026-07-09

Predictors of psychological distress among Afghan and Syrian refugee women in Houston, Texas

Abstract: Refugee mental health is shaped by a complex interplay of pre-migration trauma, migration-related hardship, and post-migration stressors. Afghan and Syrian refugees…

Date: 2026-07-09