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Association between trouble sleeping and cataract in US adults: a cross-sectional study

Abstract: To investigate the association between trouble sleeping and cataract in US adults, given the increasing global burden of cataracts and the high prevalence of sleep…

Date: 2026-04-23

Design and application of a web-based intelligent ophthalmic image analysis teaching platform

Abstract: The rapid integration of artificial intelligence (AI) into ophthalmology has created new demands for interdisciplinary education that combines clinical image…

Date: 2026-04-23

A multispecialty consensus-based red flag checklist for the early recognition of ANCA-associated vasculitis

Abstract: ANCA-associated vasculitis (AAV) is a rare multisystem autoimmune disease in which diagnostic delay remains common and contributes to organ damage. This study aimed to…

Date: 2026-04-23

Cross-national associations between adulthood stressful life events and incident heart disease: a multicohort harmonized analysis

Abstract: Whether links between adulthood stressful life events (SLEs) and heart disease are comparable across countries—and whether they follow a dose–response pattern—remains…

Date: 2026-04-23

Efficacy of immunotherapy and targeted therapy for unresectable hepatocellular carcinoma: analysis of survival curves

Abstract: Hepatocellular carcinoma is the third leading cause of cancer-related death worldwide. Because many patients present with unresectable disease at diagnosis and are…

Date: 2026-04-23

Adiponectin and phase angle in the assessment of sarcopenia in Crohn’s disease: beyond muscle mass

Abstract: Sarcopenia is a common and clinically relevant complication of Crohn’s disease (CD), reflecting the cross-link among chronic inflammation, malnutrition, and metabolic…

Date: 2026-04-23

Clinical experience using trofinetide in Rett syndrome and related MECP2 diagnosis at the children’s hospital of Philadelphia post approval

Abstract: Rett syndrome (RTT) is a rare neurodevelopmental disorder primarily caused by pathogenic variants in the MECP2 gene. Trofinetide (Daybue) became the first FDA-approved…

Date: 2026-04-23

B-cell subset changes and clinical predictors of telitacicept response in SLE patients with antiphospholipid antibody positivity: a prospective observational cohort study

Abstract: To characterize the dynamic changes in B-cell subsets in Systemic lupus erythematosus (SLE) patients with antiphospholipid antibody (aPL) positivity treated with…

Date: 2026-04-23

Differential spleen immune signatures and germinal center responses during acute infection with Orientia tsutsugamushi Karp versus Gilliam strains

Abstract: Scrub typhus is an emerging and neglected tropical disease caused by Orientia tsutsugamushi ( Ot ). Immunity in scrub typhus patients is known to be short-lived;…

Date: 2026-04-23

Ethical decision-making confidence among nurse leaders: a mixed-methods study of determinants and ethical implications

Abstract: In today’s complex healthcare environment, ethical decision-making confidence (EDMC) among nurse leaders plays a pivotal role in ensuring ethically sound nursing…

Date: 2026-04-23