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Delayed type I interferon response and the subsequent out-of-sequence cytokine signal inhibit T cell induction in non-surviving Ebola virus-infected patients

Abstract: While there is evidence that Ebola virus (EBOV) antagonizes the antiviral type I interferon (IFN-I) response, the role of IFN-I for EBOV disease remains controversial,…

Date: 2026-04-23

Status Quo analysis of an exercise therapy care model in pediatric oncology during acute therapy: perspectives from patients, parents, siblings, and staff

Abstract: In oncological pediatrics, exercise therapy is still not part of regular medical care in Germany and exercise therapy projects are currently financed by charity…

Date: 2026-04-22

A comparative study of the impact of lineal relatives versus collateral relatives donor on prognosis in haplo-HSCT for aplastic anemia

Abstract: To investigate the impact of Lineal and Collateral donors on the prognosis of recipients in haplo-HSCT for AA among relatives. A retrospective analysis of data from AA…

Date: 2026-04-22

Plasma expression of long non-coding RNA GAS5 and its prognostic significance in newly diagnosed multiple myeloma

Abstract: Long non-coding RNAs (lncRNAs) participate in pathogenesis, progression and therapy resistance in multiple myeloma (MM). Growth Arrest-Specific 5 ( GAS5 ) is a lncRNA…

Date: 2026-04-22

Clinical and immunological analysis of letermovir for preventing cytomegalovirus infection in children after hematopoietic stem cell transplantation

Abstract: The present study aimed to analyze the efficacy and safety of letermovir for preventing cytomegalovirus (CMV) infection and its impact on immune reconstitution in…

Date: 2026-04-22

Temporal trends, disparities, and ARIMA forecasts of mortality among U.S. adults with coexisting hematologic malignancy and heart failure, 1999–2023, with projections to 2033

Abstract: Hematologic malignancies (HMs) and heart failure (HF) increasingly coexist as populations age, yet population-level mortality patterns in adults with both conditions…

Date: 2026-04-22

Associations of physical activity and sedentary time with diabetic kidney disease among adults with diabetes: a multicenter population-based study

Abstract: Increased physical activity and reduced sedentary time are associated with lower risks of diabetes. However, their association with diabetic kidney disease (DKD) is…

Date: 2026-04-22

Cardiovascular and autonomic nervous system response to graded exercise in adolescents with type 1 diabetes

Abstract: Type 1 diabetes (T1D) is associated with an increased risk of cardiovascular and autonomic complications. Although cardiopulmonary exercise testing (CPET) is a valuable…

Date: 2026-04-22

Development and validation of a multi-center nomogram for the presence of diabetic retinopathy in patients with type 2 diabetes: incorporating homocysteine, glycemic, lipid, and renal markers

Abstract: To develop and validate a nomogram that integrates plasma homocysteine with glycemic, lipid, and renal markers for estimating the probability of prevalent diabetic…

Date: 2026-04-22

COVID-19 pandemic and thyroid diseases

Abstract: The COVID-19 pandemic has been associated with various autoimmune manifestations. Several studies have suggested a potential association between COVID-19 and thyroid…

Date: 2026-04-22