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Low baseline HbA1c and reduced eGFR are associated with relatively unfavorable body recomposition after SGLT2 inhibitor therapy in type 2 diabetes

Abstract: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) improve glycemic control and promote weight loss, but their…

Date: 2026-08-27

Effectiveness and renal safety of dupilumab in the treatment of moderate-to-severe atopic dermatitis patients with chronic kidney disease stages 4–5: a real-world cohort study in China

Abstract: While dupilumab is widely used for atopic dermatitis (AD), its safety and effectiveness in patients with severe renal failure remain insufficiently studied. To evaluate…

Date: 2026-08-27

CFTR mutations and genotypic patterns among cystic fibrosis patients with allergic bronchopulmonary aspergillosis: analysis from a tertiary care center in Saudi Arabia

Abstract: Cystic fibrosis (CF) is a multisystem disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Allergic bronchopulmonary…

Date: 2026-08-27

Longitudinal developmental trajectories of weight-standardized lung function in preterm (28–36?+?6 weeks) vs. term infants and independent perinatal risk factors: a single-center prospective cohort study

Abstract: To compare weight-normalized tidal lung function trajectories from corrected 40 weeks to 6 months postmenstrual age (PMA) between preterm infants (28–36?+?6 weeks…

Date: 2026-08-27

Development and validation of a predictive model for myocardial injury in children with pneumonia based on interpretable machine learning

Abstract: This study aimed to identify independent factors for pneumonia-related myocardial injury in children, and construct and validate a risk prediction model and…

Date: 2026-08-27

Application of multidisciplinary collaborative nursing intervention based on King’s Goal Attainment Theory in medical transition readiness of adolescents with chronic kidney disease

Abstract: To explore the application effect of multidisciplinary collaborative nursing intervention based on King's Goal Attainment Theory on medical transition readiness in…

Date: 2026-08-27

Phosphoproteomic analysis in a mouse model reveals ERK signaling as a key modulator of inflammatory response in nasal mucosa associated with childhood allergic rhinitis

Abstract: Childhood allergic rhinitis (AR) is a multifactorial condition arising from the interplay between genetic predisposition and environmental exposures. Although protein…

Date: 2026-08-27

Speed-related increases in plantar tissue stress without affected-side laterality in individuals with unilateral shoulder dislocation

Abstract: Unilateral shoulder dislocation may be accompanied by altered upper-limb use and trunk-control strategies; however, whether individuals with unilateral shoulder…

Date: 2026-08-27

Development and internal validation of a prognostic nomogram for recurrence in chronic rhinosinusitis with nasal polyps after functional endoscopic sinus surgery

Abstract: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently recurs after functional endoscopic sinus surgery (FESS). This study aimed to develop and internally validate…

Date: 2026-08-27

What limits a bystander’s action to perform cardiopulmonary resuscitation in China? Insights from a cross-sectional study conducted in Shaanxi Province

Abstract: Rate of bystander-initiated cardiopulmonary resuscitation (CPR) remains critically low in China. Identifying the underlying reasons may help reduce mortality from…

Date: 2026-08-27