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Faricimab in neovascular age-related macular degeneration: aqueous humor cytokine profiling and biomarker correlations

Abstract: To investigate aqueous humor cytokine profile changes in neovascular age-related macular degeneration (nAMD) patients before and after intravitreal faricimab injection,…

Date: 2026-08-21

Integrated histopathology and single-cell transcriptomics reveal distinct pathological features and foamy macrophage characteristics in spinal tuberculosis and brucellar spondylitis

Abstract: Spinal tuberculosis (STB) and brucellar spondylitis (BS) show substantial overlap in clinical and imaging manifestations, but their local immunopathological programs and…

Date: 2026-08-21

Interpretable machine learning analysis of the impact of tranexamic acid combined with antibiotics on renal function and its risk factors in hip replacement surgeries

Abstract: Early prediction of renal function changes in patients undergoing hip replacement surgery enables timely intervention for acute kidney injury and acute renal failure,…

Date: 2026-08-21

Preoperative neutrophil-to-lymphocyte ratio is associated with amputation level progression in patients with diabetic foot

Abstract: Amputation-level progression after below-knee amputation (BKA) is associated with functional and psychological burden in diabetic foot disease. We evaluated the…

Date: 2026-08-21

Treatment time metrics and functional outcomes after endovascular thrombectomy in routine clinical practice

Abstract: Randomised clinical trials have shown that functional outcomes after acute ischaemic stroke decline with each hour of delay to endovascular treatment. However, these…

Date: 2026-08-21

Distress disclosure and health behaviours in patients with stroke: a theory-informed serial mediation model of social support, self-efficacy, and self-management

Abstract: To examine the association between distress disclosure and health behaviours among patients with stroke and to test whether social support, self-efficacy and…

Date: 2026-08-21

Roles of sex and SP-A genetic variants in modulating multiorgan injuries post viral infection

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can lead to acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), and multi-organ…

Date: 2026-08-21

Analysis of latent profiles of stressors and their influencing factors in patients with breast cancer undergoing postoperative chemotherapy: a mixed-methods study

Abstract: To explore the heterogeneity of stress experiences, identify latent stressor profiles, and analyze their influencing factors in patients with breast cancer undergoing…

Date: 2026-08-21

Evaluating risk factors affecting chronic wound healing: a comprehensive analysis using logistic regression and neural network models

Abstract: Chronic wounds impose immense burdens and suffering on patients, with healing governed by a complex blend of physiological, social, and psychological components. This…

Date: 2026-08-21

Prognostic impact of CD123 overexpression on the outcome of pediatric acute myeloid leukemia

Abstract: Despite advances in acute myeloid leukemia (AML) therapy, outcomes remain poor. CD123 overexpression influences proliferation and enhanced survival of leukemic cells.…

Date: 2026-08-21