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Treatment of anti-GAD65 antibody-positive epilepsy and cerebellar ataxia with efgartigimod: a case report and literature review

Abstract: Anti-glutamic acid decarboxylase 65 (GAD65) antibody-associated neurological syndrome is a rare autoimmune disorder with heterogeneous clinical manifestations, including…

Date: 2026-08-04

Defining nature, responses and drivers of regulatory- and conventional CD4 + T cells in the human term decidua

Abstract: During mammalian pregnancy, a maternal immunoregulatory network develops in the decidua that fosters fetal development, maintains tolerance to fetal antigens and…

Date: 2026-08-04

Metastatic organ distribution characteristics and prognosis in patients with non-small cell lung cancer

Abstract: Non-small cell lung cancer (NSCLC) is often diagnosed at advanced stages, with distant metastasis being the leading cause of death. However, the distribution patterns of…

Date: 2026-08-04

Enhancing multimodal survival prediction: tri-modal learning with clinical knowledge integration via state space models

Abstract: Accurate survival prediction is crucial for precision oncology, yet it faces challenges due to the neglect of clinical priors and high computational complexity. We…

Date: 2026-08-04

Coordinated dynamics of circulating neutrophils, regulatory T lymphocytes, myeloid derived suppressor cells and distinct granulocytic subsets reveal a complex immune network in metastatic colorectal cancer

Abstract: Circulating immune cells serve as readily accessible biomarkers in cancer patients. Some of them, such as neutrophils, lymphocytes as well as the neutrophil to…

Date: 2026-08-04

Deep learning models based on CT predict prognosis in patients with locally advanced esophageal squamous cell carcinoma who received neoadjuvant immunotherapy and chemotherapy

Abstract: Neoadjuvant immunotherapy and chemotherapy (NICT) has emerged as the standard pharmacological intervention for locally advanced esophageal squamous cell carcinoma…

Date: 2026-08-04

Predictors of survival in triple-negative breast cancer patients treated with neoadjuvant chemotherapy, surgery, and radiotherapy

Abstract: Triple-negative breast cancer (TNBC) is known for its heterogeneity. Due to the small sample sizes in prior studies, there is limited understanding of whether different…

Date: 2026-08-04

Electric field effects of pulsed field ablation through adjacent non-cardiac tissues in an in vitro hybrid model

Abstract: Endocardial ablation of atrial arrhythmias may occasionally produce insufficient lesion depth. Pulsed-field ablation (PFA) may generate measurable electroporation…

Date: 2026-08-04

Social isolation, loneliness, disability progression, and mortality among older adults with cardiac disease: a longitudinal NHATS study

Abstract: Cardiac disease is the leading cause of morbidity and mortality among older adults, yet the psychosocial pathways through which it accelerates functional decline remain…

Date: 2026-08-04

Global research trends and hotspots evolution in type 2 diabetes mellitus complicated with coronary heart disease: a bibliometric analysis from 2016 to 2026

Abstract: The comorbidity burden of type 2 diabetes mellitus complicated with coronary heart disease is steadily increasing. However, there is a lack of systematic mapping of the…

Date: 2026-08-04