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Efficacy of BEAM versus BeEAM conditioning regimens in autologous hematopoietic stem cell transplantation for diffuse large B-cell lymphoma: a retrospective single-center study

Abstract: The BEAM regimen (carmustine, etoposide, cytarabine, melphalan) is the standard conditioning regimen for autologous hematopoietic stem cell transplantation (auto-HSCT)…

Date: 2026-08-03

Oncolytic HSV1716 attenuates tumor-killing activity of infected primary NK cells

Abstract: Oncolytic herpes simplex virus type-1 (HSV1)–based therapies engage innate immune responses, including natural killer (NK) cells, which are regarded as antiviral…

Date: 2026-08-03

Wiskott-Aldrich syndrome: clinical, immunological, and genetic characterization of the first Moroccan cohort

Abstract: Wiskott–Aldrich syndrome (WAS) is a rare X-linked inborn error of immunity characterized by thrombocytopenia, eczema, and recurrent infections, with additional risks of…

Date: 2026-08-03

Association between UMAP-identified body composition phenotypes and metabolic dysfunction-associated steatotic liver disease in the general population of China

Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD) poses a critical global health challenge, yet traditional anthropometric indices fail to precisely…

Date: 2026-08-03

ANGPTL2 overexpression promotes angiogenic responses in human retinal microvascular endothelial cells with accompanying integrin ?5?1 molecular changes

Abstract: Diabetic retinopathy (DR) is a leading cause of preventable vision loss worldwide, characterized by retinal microvascular dysfunction and progressive angiogenic…

Date: 2026-08-03

Bilateral adrenal adenomas presenting with ACTH-independent Cushing’s syndrome and primary aldosteronism: diagnostic insights from multi-steroid adrenal venous sampling

Abstract: Primary aldosteronism (PA) is the most prevalent cause of secondary hypertension (HTN), and adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome (CS)…

Date: 2026-08-03

Spatial transcriptomic analysis identifies a necroptosis-prone thyroid follicular cell state in Hashimoto’s thyroiditis

Abstract: Hashimoto’s Thyroiditis (HT) is the leading cause of primary hypothyroidism, characterized by progressive thyroid follicular cell (TFC) loss and diffuse lymphocytic…

Date: 2026-08-03

Metabolic correlates of endoscopy-confirmed reflux esophagitis in hospital-based patients with type 2 diabetes mellitus

Abstract: Reflux esophagitis (RE) is an endoscopy-defined manifestation of gastroesophageal reflux disease and may be related to metabolic disturbance in type 2 diabetes mellitus…

Date: 2026-08-03

Assessment of biomarkers of thyroid hormone action across three thyroid hormone replacement regimens in hypothyroidism

Abstract: A common concern during thyroid hormone replacement therapy is over-substitution leading to increased risk of primarily osteoporotic fracture, and adverse cardiac…

Date: 2026-08-03

Temporal trends in long-term relative survival of cutaneous verrucous carcinoma: a period analysis from a large-scale SEER-based cohort

Abstract: Cutaneous verrucous carcinoma (CVC) is a rare, well-differentiated variant of squamous cell carcinoma characterized by slow progression, local invasiveness, and limited…

Date: 2026-08-03