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Integration of ultra-widefield optical coherence tomography angiography images and clinical indicators for identifying early-stage diabetic retinopathy in type 2 diabetes

Abstract: Diabetic retinopathy (DR) is a common microvascular complication of diabetes and a leading cause of irreversible vision loss among working-age adults, making early…

Date: 2026-09-24

Psychological resilience profiles and their psychosocial correlates among adults with prediabetes: a latent profile analysis

Abstract: Prediabetes is a high-risk metabolic state with a rapidly increasing global prevalence. Beyond its metabolic consequences, individuals with prediabetes face an elevated…

Date: 2026-09-24

Risk factors and nomogram for gallbladder stones in patients with type 2 diabetes mellitus: a retrospective study based on LASSO regression

Abstract: To investigate factors associated with gallstone occurrence in patients with type 2 diabetes and to establish a nomogram for predicting gallstone presence in this…

Date: 2026-09-24

Cholesterol-modified prognostic nutritional index: a novel nutritional biomarker for prevalent diabetic retinopathy in patients with type 2 diabetes mellitus

Abstract: To investigate the association and dose–response relationship between the cholesterol-modified prognostic nutritional index (CPNI) and diabetic retinopathy (DR) in…

Date: 2026-09-24

Conditional myeloid-specific deletion of Ube2n hinders YUMM1.7 melanoma growth

Abstract: The role of UBE2N in myeloid cell-mediated immune suppression in cancer remains undefined. Here, we examined the function of UBE2N in myeloid cell-mediated tumor…

Date: 2026-09-24

Periodic fever, aphthous stomatitis, pharyngitis, adenitis: clinical manifestations, response to steroids, and a practice of online diagnosis and follow-up

Abstract: Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome, although not rare, is frequently underdiagnosed. This might be related to the fact that…

Date: 2026-09-24

Earlier bedtime at 1.5?years is associated with greater height gain at 3?years of age: a nationwide birth cohort study of the Japan environment and children’s study

Abstract: Previous studies have shown inconsistent associations between sleep duration and height gain in early childhood. The relationships of bedtime and nighttime awakenings…

Date: 2026-09-24

Comparative effectiveness and safety of topiramate versus amitriptyline for the prophylactic management of chronic migraine: a prospective comparative study

Abstract: Chronic migraine is a chronic disabling neurological disease and has a significant impact on quality of life. Topiramate and amitriptyline are commonly used for migraine…

Date: 2026-09-24

Educational environment perceptions across curriculum formats: structural associations among DREEM domains and academic self-perceptions

Abstract: Team-Based Learning (TBL) is increasingly used in health professions education; however, the Dundee Ready Education Environment Measure (DREEM) has rarely been formally…

Date: 2026-09-24

Association of the systemic immune-inflammation index with consciousness disturbance in cerebral venous sinus thrombosis: a retrospective cohort study

Abstract: Consciousness disturbance (CD) is a severe neurological manifestation of cerebral venous sinus thrombosis (CVST), but the association between the systemic…

Date: 2026-09-24