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Diagnostic value of tubular and glomerular biomarkers across different stages of kidney injury in patients with type 2 diabetic nephropathy

Abstract: Diabetic nephropathy (DN) remains a major cause of chronic kidney disease in patients with type 2 diabetes mellitus (T2DM), yet conventional markers incompletely capture…

Date: 2026-06-18

Acute glucose stimulation drives coordinated translational reprogramming in primary pancreatic islets: from global remodeling to fine-tuned insulin synthesis

Abstract: Pancreatic beta cells must rapidly escalate protein synthesis to maintain systemic glucose homeostasis. While the transcriptional responses are well characterized, the…

Date: 2026-06-18

The levels of vascular endothelial cells and endothelium-dependent vasomotor cytokines in children with essential hypertension: a case-control study

Abstract: Circulating endothelial cells (CECs), endothelial progenitor cells (EPCs) and endothelium-dependent vasomotor cytokines are important in maintaining endothelial function…

Date: 2026-06-18

Association between glucolipid metabolic indicators and the risk of suspected precocious puberty in children living with obesity: a retrospective cohort study

Abstract: To investigate the association between glucolipid metabolic indicators and suspected precocious puberty (PP) in children living with obesity. This retrospective…

Date: 2026-06-18

Identifying predictors of use of mental health services and supports during the COVID-19 pandemic: an analysis of the CHILD COVID-19 Add-on Study

Abstract: The aim of this work was to explore the rate of and factors associated with the use of mental health services and supports (MHSS) in a Canadian cohort of children and…

Date: 2026-06-18

Impact of high disease activity on damage accrual and disease outcomes in childhood-onset systemic lupus erythematosus

Abstract: The impact of the duration and cumulative high disease activity on damage accrual in childhood-onset SLE (cSLE) is less well established. This study aimed to assess the…

Date: 2026-06-18

Age differences in susceptibility to stroke-related health misinformation on social media: the role of prior experience and corrective feedback

Abstract: The rapid dissemination of complex health-related misinformation poses a critical threat to public health management and healthy lifestyles. To address this infodemic,…

Date: 2026-06-18

The “5–4-3” model for weight management in psychiatric inpatients: a single-arm pre-post evaluation

Abstract: Comprehensive weight management remains an understudied yet critical component of inpatient psychiatric care, particularly for individuals presenting with overweight or…

Date: 2026-06-18

Mobile internet use, physical exercise and depression levels: mediating mechanism and empirical evidence

Abstract: Mental health has increasingly become a central component of national health agendas worldwide, aligning with the World Health Organization’s commitment to comprehensive…

Date: 2026-06-18

Work–family conflict and occupational fatigue among clinical nurses in China: a latent profile analysis

Abstract: To examine the impact of work–family conflict (WFC) on occupational fatigue among clinical nurses in China and to identify the heterogeneity of occupational fatigue…

Date: 2026-06-18