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Microbiota metabolite butyrate alleviates intestinal inflammation associated with enhanced autophagy-related signaling in DSS-induced colitis

Abstract: The incidence of inflammatory bowel disease (IBD) has been demonstrated to be increased over recent decades. Butyrate derived from the gut microbiota is known to be…

Date: 2026-06-17

Increased severity and relapse rate in adult anti-nuclear matrix protein 2 antibody positive myositis patients with distal limb weakness: a retrospective study in China

Abstract: This study aimed to examine the clinical features and prognosis of patients with distal limb weakness in anti-nuclear matrix protein 2 antibody (anti-NXP2) positive…

Date: 2026-06-17

The aMAP score improves discrimination of prognostic models in hepatocellular carcinoma after radiofrequency ablation

Abstract: The aMAP score has proven a reliable model for predicting the risk of hepatocellular carcinoma (HCC) development in patients with various types of hepatitis, but its…

Date: 2026-06-17

Admission hyperglycemia, estimated glomerular filtration rate and outcome of acute ischemic stroke after mechanical thrombectomy: a mediation analysis

Abstract: Multiple factors influence the efficacy of mechanical thrombectomy (MT) in patients with acute ischemic stroke. This study aimed to clarify the association between…

Date: 2026-06-17

Dysphagia in patients with severe stroke: influencing factors and coping strategies

Abstract: Dysphagia is a common and serious complication in patients with severe stroke. This study aimed to identify independent risk factors for dysphagia in this population,…

Date: 2026-06-17

Targeted replacement of human ?? TCR in mice enhances antigen-specific B cell immunity

Abstract: The humanized (Hu) gamma delta (??) T cell receptor (TCR) -T1 (?? HuTCR-T1) mouse model represents a novel and versatile platform for investigating human-like immune…

Date: 2026-06-17

Assessment of vaccine information accuracy across large language models

Abstract: Use of Large Language Models (LLMs) as a health information source is on the rise. As the amount of people willing to self-diagnose with the tools’ help is increasing,…

Date: 2026-06-17

Distinct IgM and IgG autoantibody profiles characterize incomplete and classified systemic autoimmune diseases

Abstract: Incomplete lupus erythematosus (ILE) and non-Sjögren’s disease sicca (nSjD-sicca) are clinically heterogeneous, incompletely classified autoimmune conditions that share…

Date: 2026-06-17

Knowledge localization is associated with higher performance of domestic large language models in a Chinese radiation oncology examination

Abstract: The rapid evolution of large language models has demonstrated human-level proficiency in general English-language medical examinations, yet their applicability in highly…

Date: 2026-06-17

Efficacy and safety of radiotherapy combined with chemoimmunotherapy versus chemoimmunotherapy alone as first-line treatment for metachronous oligorecurrent esophageal squamous cell carcinoma

Abstract: Metachronous oligorecurrence is usually defined as oligometastatic disease diagnosed more than 6 months after primary tumor diagnosis in the absence of active systemic…

Date: 2026-06-17