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Critical shortage of gastrointestinal physician density in the USA: impact on mortality from upper gastrointestinal bleeding

Abstract: Upper gastrointestinal bleeding (UGIB) continues to pose a significant burden on the national healthcare system. However, geographical patterns of UGIB-associated…

Date: 2026-06-15

Relative increase of memory B-cell subsets under s.c. B-cell-depleting therapies in multiple sclerosis

Abstract: Monoclonal antibodies targeting CD20-expressing B cells constitute effective therapies for people with multiple sclerosis (pwMS) and can be administered intravenously…

Date: 2026-06-15

Summary of the best evidence for non-pharmacological management of dysphagia in Parkinson’s disease patients

Abstract: This study systematically synthesizes the best available evidence for the non-pharmacological management of swallowing disorders in Parkinson’s disease, establishing an…

Date: 2026-06-15

Cerebrovascular thrombosis during pediatric ALL therapy: a case series highlighting temporal association with PEG-asparaginase exposure

Abstract: Cerebrovascular thrombosis is an uncommon but potentially life-threatening complication of chemotherapy in children with acute lymphoblastic leukemia (ALL). Although…

Date: 2026-06-15

Baseline neutrophil-to-lymphocyte ratio combined with SLEDAI predicts lupus low disease activity state at 1 year: a cohort study

Abstract: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease in which treat-to-target management increasingly emphasizes attainment of Lupus Low Disease…

Date: 2026-06-15

Transdermal entry of a non-pathogenic filamentous fungus Aspergillus oryzae induces an immunomodulatory response in skin-draining lymph nodes

Abstract: The immune response to non-pathogenic fungi entering the skin remains largely unknown. In this study, we focused on the fermentative filamentous fungus Aspergillus…

Date: 2026-06-15

Network analysis identifies core fear symptoms as screening clues for post-PCI rehabilitation in patients with acute myocardial infarction

Abstract: Acute myocardial infarction is a leading cause of death among cardiovascular patients. Fear following percutaneous coronary intervention (PCI) can impede patient…

Date: 2026-06-15

Congestion, but not low cardiac output, is independently associated with acute kidney injury following contrast agent exposure

Abstract: Contrast-associated acute kidney injury (CA-AKI) is frequently associated with adverse outcomes. Renal perfusion gradient is central to glomerular filtration. While…

Date: 2026-06-15

Single-catheter radiofrequency pulmonary vein isolation for atrial fibrillation: a comparative evaluation

Abstract: Circular mapping catheters (CMC) are used to confirm pulmonary vein isolation (PVI) in radiofrequency (RF) ablation for atrial fibrillation (AF), but may be unnecessary…

Date: 2026-06-15

Disease characteristics, treatment, and outcomes in Chinese chronic lymphocytic leukemia patients following BTK inhibitor discontinuation: a multicenter real-world study

Abstract: Utilization of novel Bruton tyrosine kinase inhibitors (BTKi) has become common for treating CLL/SLL patients, yet limited evidence exists on the clinical…

Date: 2026-06-12