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Acetylcholine receptor antibody-positive myasthenia gravis and Kennedy’s disease overlap syndrome: a case report and literature review

Abstract: To investigate the clinical characteristics and electromyographic findings of a patient with acetylcholine receptor (AChR) antibody-positive myasthenia gravis (MG)…

Date: 2026-06-11

Effectiveness and safety of avelumab maintenance in patients aged ?75 years with advanced urothelial cancer: a sub-analysis of the meet-URO 25 (MALVA) study

Abstract: Avelumab maintenance therapy is an established therapeutic approach for patients with advanced urothelial carcinoma (UC) whose disease has not progressed after…

Date: 2026-06-11

Subsite-specific benefit of induction chemoimmunotherapy in HPV-negative oropharyngeal squamous cell carcinoma

Abstract: To evaluate whether the addition of immune checkpoint inhibitors (ICIs) to induction chemotherapy improves outcomes in HPV-negative oropharyngeal squamous cell carcinoma…

Date: 2026-06-11

Psychological predictors of functioning in patients with asthma

Abstract: Psychological characteristics significantly modify the impact of asthma on overall functioning. The emotional burden associated with the disease interacts with somatic…

Date: 2026-06-11

Latent transition analysis of resilience in breast cancer patients and its association with sense of meaning in life: a longitudinal follow - up study

Abstract: Breast cancer is a highly prevalent malignant tumor among women, showing a trend of younger onset. The disease - related stress can easily trigger an existential crisis…

Date: 2026-06-11

Utility of miRNA biomarkers in patients with acute myocardial infarction (UNIAMI)—results from a prospective pilot study

Abstract: Acute myocardial infarction (AMI) is a leading cause of death worldwide, occurring earlier and more severely in South Asian populations. Circulating microRNAs (miRNAs)…

Date: 2026-06-11

Association between HLA-DRB1*04:05 and the efficacy of immune checkpoint inhibitors for patients with advanced cancer

Abstract: Tumor cells use immune checkpoint proteins such as programmed cell death 1 to escape immunological defenses. Immune checkpoint inhibitors (ICIs) that target these…

Date: 2026-06-10

Clinical characteristics, management, and prognosis of pembrolizumab-induced hypophysitis: retrospective analysis based on case reports

Abstract: Pembrolizumab-induced hypophysitis is a rare but clinically important immune-related adverse event. Its clinical features and long-term outcomes are not fully defined.…

Date: 2026-06-10

Association of prognostic nutritional index with the risk of all-cause mortality and cardiovascular events in patients with diabetes-related foot ulcers: a non-linear relationship mediated by eGFR

Abstract: Diabetes-related foot ulcers (DFU), a severe complication of diabetes, is strongly associated with high mortality. Although the prognostic nutritional index (PNI) has…

Date: 2026-06-10

Identification of potential biomarkers related to mannose metabolism in keloids: analysis of integrated bulk RNA-seq and scRNA-seq

Abstract: Keloid (KD) is a benign cutaneous fibrotic disorder characterized by excessive proliferation of dermal fibroblasts. Mannose plays a key role in cellular metabolism, yet…

Date: 2026-06-10