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A combined therapeutic approach: extracorporeal shock wave therapy and botulinum toxin in multiple sclerosis-related spasticity

Abstract: Focal extracorporeal shock wave therapy (fESWT) is a non-invasive treatment for spasticity in neurological disorders; evidence in multiple sclerosis (MS) is limited. The…

Date: 2026-06-16

Transcriptomic profiling and IgM and IgT repertoire dynamics in rainbow trout gills following primary and secondary challenge with Lactococcus petauri

Abstract: Fish mucosal tissues lack the organized lymphoid structures present in mammals. Although this is also true for the gills, with the gill-associated lymphoid tissue…

Date: 2026-06-16

An expression signature of 19 human endogenous retroviruses identifies immunogenic luminal breast cancers likely to respond to immunotherapy

Abstract: Human endogenous retroviruses (HERVs) are single-stranded RNA viruses that have integrated into the human germline, and whose sequences represent approximately 8% of the…

Date: 2026-06-16

The CSF1 + tumor cell–SPP1 + macrophage axis drives gastric cancer progression and immunotherapy resistance

Abstract: Gastric cancer (GC) remains a leading cause of global cancer mortality, characterized by profound heterogeneity. While immune checkpoint blockade (ICB) has emerged as a…

Date: 2026-06-16

Autologous stem cell transplantation for pediatric solid tumors in a resource-limited setting: a single-center experience of 15 years

Abstract: Autologous hematopoietic stem-cell transplant(ASCT) following high-dose chemotherapy is an established treatment for selected pediatric solid tumors. However, data from…

Date: 2026-06-16

A deep learning-based prognostic model for diffuse large B-cell lymphoma incorporating PET/CT imaging features

Abstract: This study aims to create and validate a prognostic prediction model that leverages deep features derived from PET/CT imaging to support personalized precision treatment…

Date: 2026-06-16

A nomogram as a predictive tool for lymph node metastasis in papillary thyroid carcinoma

Abstract: Lymph node metastasis is the most prevalent form of spread in thyroid cancer, with surgical intervention and prophylactic cervical lymph node dissection being the…

Date: 2026-06-16

Relationships between anxiety–depression, perceived social support, and in-hospital outcomes among patients with acute myocardial infarction

Abstract: To examine associations between early anxiety–depression symptoms, perceived social support, and in-hospital outcomes in patients with acute myocardial infarction (AMI).…

Date: 2026-06-16

Impact of the longitudinal evolution of impaired fasting glucose on cardio-kidney-metabolic multimorbidity

Abstract: To characterize longitudinal impaired fasting glucose (IFG) evolution patterns and evaluate their associations with the risk of incident cardio-kidney-metabolic (CKM)…

Date: 2026-06-16

Closing the quality gap: analysis of implementation barriers and interventions for postoperative exercise rehabilitation for patients with radiofrequency ablation for atrial fibrillation

Abstract: Atrial fibrillation patients often experience issues such as recurrence and reduced exercise tolerance following radiofrequency catheter ablation, which adversely affect…

Date: 2026-06-16