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Congestion, but not low cardiac output, is independently associated with acute kidney injury following contrast agent exposure

Abstract: Contrast-associated acute kidney injury (CA-AKI) is frequently associated with adverse outcomes. Renal perfusion gradient is central to glomerular filtration. While…

Date: 2026-06-15

Single-catheter radiofrequency pulmonary vein isolation for atrial fibrillation: a comparative evaluation

Abstract: Circular mapping catheters (CMC) are used to confirm pulmonary vein isolation (PVI) in radiofrequency (RF) ablation for atrial fibrillation (AF), but may be unnecessary…

Date: 2026-06-15

Disease characteristics, treatment, and outcomes in Chinese chronic lymphocytic leukemia patients following BTK inhibitor discontinuation: a multicenter real-world study

Abstract: Utilization of novel Bruton tyrosine kinase inhibitors (BTKi) has become common for treating CLL/SLL patients, yet limited evidence exists on the clinical…

Date: 2026-06-12

Mortality trends in diabetes with proxy-defined steatotic liver disease in the United States, 1999–2023

Abstract: To characterize U.S. mortality trends for diabetes mellitus (DM), proxy-defined metabolic dysfunction–associated steatotic liver disease (MASLD), and deaths listing both…

Date: 2026-06-12

Feminizing hormone therapy using GnRH agonists as antiandrogens is not associated with adverse metabolic and bone effects in adult transgender women

Abstract: Gender-affirming hormone therapy (GAHT) effectively alleviates gender dysphoria. However, its effect on metabolic and bone health is not well-established. The goal of…

Date: 2026-06-12

Development and validation of an interpretable machine learning model for predicting central lymph node metastasis in papillary thyroid cancer

Abstract: To develop and validate a machine learning-based prediction model for central lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC) patients using routine…

Date: 2026-06-12

A multi-method study on GPs’ perspectives on Lipoprotein(a) as an actionable cardiovascular risk factor

Abstract: Elevated Lipoprotein(a) [Lp(a)] is a common hypercholesterolaemia disorder that requires continuity of care from primary care doctors, yet elevated Lp(a) is a highly…

Date: 2026-06-12

Development and validation of a machine learning-based predictive model for carotid plaque in type 2 diabetes

Abstract: Carotid plaque is a critical risk factor for cardiovascular disease and reflects the extent of the atherosclerotic burden. Compared with non-diabetic individuals,…

Date: 2026-06-12

Temporal and anatomic determinants of central-line–associated bloodstream infection risk in a tertiary PICU: a 3-year time-to-event and competing-risk analysis

Abstract: Central line–associated bloodstream infections remain a major cause of preventable morbidity in pediatric intensive care units, yet most prevention strategies treat…

Date: 2026-06-12

Efficacy and safety of sini powder combined with Xiaoxianxiong decoction for adolescent depression with liver qi stagnation and phlegm-heat obstruction syndrome: a randomized controlled trial

Abstract: To assess efficacy and safety of Sini San combined with Xiaoxianxiong Tang as add-on therapy for adolescents (12–18 years) with liver qi stagnation and phlegm-heat…

Date: 2026-06-12