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Beyond BMI: L4–L5 visceral-to-subcutaneous fat ratio on CT predicts impaired wound healing after posterior lumbar fusion—A retrospective study

Abstract: Obesity is a recognized risk factor for postoperative complications after spine surgery, but body mass index (BMI) does not capture regional fat distribution. The…

Date: 2026-06-15

Evaluation of clinical effects and plasma metabolomic profiles after the administration of grapiprant in dogs affected by osteoarthritis: a prospective, off–on–off, clinical study

Abstract: Osteoarthritis (OA) is a prevalent cause of chronic pain and impaired mobility in dogs. Grapiprant, an EP4 prostaglandin receptor antagonist, represents a novel…

Date: 2026-06-15

The clinical value of analyzing predictive models for gastric function and gastric organic lesions

Abstract: To explore the clinical value of the predictive models for gastric function and gastric organic lesions. Clinical data from 1,677 patients with digestive tract-related…

Date: 2026-06-15

Critical shortage of gastrointestinal physician density in the USA: impact on mortality from upper gastrointestinal bleeding

Abstract: Upper gastrointestinal bleeding (UGIB) continues to pose a significant burden on the national healthcare system. However, geographical patterns of UGIB-associated…

Date: 2026-06-15

Relative increase of memory B-cell subsets under s.c. B-cell-depleting therapies in multiple sclerosis

Abstract: Monoclonal antibodies targeting CD20-expressing B cells constitute effective therapies for people with multiple sclerosis (pwMS) and can be administered intravenously…

Date: 2026-06-15

Summary of the best evidence for non-pharmacological management of dysphagia in Parkinson’s disease patients

Abstract: This study systematically synthesizes the best available evidence for the non-pharmacological management of swallowing disorders in Parkinson’s disease, establishing an…

Date: 2026-06-15

Cerebrovascular thrombosis during pediatric ALL therapy: a case series highlighting temporal association with PEG-asparaginase exposure

Abstract: Cerebrovascular thrombosis is an uncommon but potentially life-threatening complication of chemotherapy in children with acute lymphoblastic leukemia (ALL). Although…

Date: 2026-06-15

Baseline neutrophil-to-lymphocyte ratio combined with SLEDAI predicts lupus low disease activity state at 1 year: a cohort study

Abstract: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease in which treat-to-target management increasingly emphasizes attainment of Lupus Low Disease…

Date: 2026-06-15

Transdermal entry of a non-pathogenic filamentous fungus Aspergillus oryzae induces an immunomodulatory response in skin-draining lymph nodes

Abstract: The immune response to non-pathogenic fungi entering the skin remains largely unknown. In this study, we focused on the fermentative filamentous fungus Aspergillus…

Date: 2026-06-15

Network analysis identifies core fear symptoms as screening clues for post-PCI rehabilitation in patients with acute myocardial infarction

Abstract: Acute myocardial infarction is a leading cause of death among cardiovascular patients. Fear following percutaneous coronary intervention (PCI) can impede patient…

Date: 2026-06-15