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Isolated prenatal foramen ovale closure or restriction presenting after birth: a distinct, under-recognized clinical condition

Abstract: The foramen ovale (FO) plays a central role in fetal circulation. Prenatal FO closure or restriction is well-characterized in fetuses and in neonates with congenital…

Date: 2026-06-05

The impact of antinuclear antibodies and complement levels in the prognosis of pregnant women within the antiphospholipid syndrome spectrum

Abstract: To assess the prevalence and clinical impact of antinuclear antibodies (ANA) and low complement levels on fetal–maternal outcomes in pregnant women within the spectrum…

Date: 2026-06-05

Vaginal dysbiosis and inflammatory signatures in preterm labor: an integrated model for predicting preterm birth

Abstract: Preterm birth (PTB) is a major cause of neonatal morbidity and mortality, with vaginal microbiome dysbiosis and local immune responses implicated in its pathogenesis.…

Date: 2026-06-05

Utility of prenatal trio whole-exome sequencing and methylation-specific multiplex ligation-dependent probe amplification in the evaluation of fetal growth restriction

Abstract: This study aimed to explore the application value of prenatal trio whole-exome sequencing (trio-WES) and methylation-specific multiplex ligation-dependent probe…

Date: 2026-06-05

Postoperative analgesic efficacy of intertransverse process block vs. erector spinae plane block in total laparoscopic hysterectomy: a randomized double-blind trial

Abstract: Due to multiple factors, patients will experience significant postoperative pain following laparoscopic total hysterectomy (TLH), predominantly manifesting as visceral…

Date: 2026-06-05

Single point insulin sensitivity estimator index and incident impaired fasting glucose in Chinese adults: a retrospective cohort study

Abstract: Insulin resistance is the core pathophysiological mechanism underlying the development of impaired fasting glucose (IFG) and diabetes mellitus. The SPISE index is a…

Date: 2026-06-05

Additive impulsivity and emotion dysregulation in adolescents with comorbid bipolar and substance use disorder: a cross-sectional factorial study

Abstract: Comorbid bipolar disorder (BD) and substance use disorder (SUD) in adolescence is associated with poor clinical outcomes, yet the independent and interactive…

Date: 2026-06-05

Nutritional status and postoperative recovery outcomes in patients undergoing orthopedic surgery

Abstract: Malnutrition is a prevalent yet often overlooked phenomenon among orthopedic patients, and it can adversely affect postoperative recovery and functional outcomes. To…

Date: 2026-06-05

Biportal endoscopic spinal surgery for thoracic ossification of the ligamentum flavum: a study of different classification types and surgical outcomes

Abstract: This study aimed to assess potential differences in the clinical effectiveness of biportal endoscopic spinal surgery (BESS) for treating various axial classifications of…

Date: 2026-06-05

High-Risk foreign body ingestion in children: clinical features and endoscopic outcomes

Abstract: To evaluate clinical features and endoscopic outcomes in children with high-risk upper gastrointestinal (GI) foreign bodies, stratified by object type. We…

Date: 2026-06-05