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A multicenter prospective cohort study developing and validating a SIRI-based machine learning model and simplified risk score for predicting postherpetic neuralgia

Abstract: Postherpetic neuralgia (PHN) is the most common and severe complication of herpes zoster (HZ), and early identification of high-risk patients remains a major clinical…

Date: 2026-06-05

Residual inflammation in the cerebrospinal fluid after short- and long-term natalizumab treatment in relapsing-remitting multiple sclerosis

Abstract: Natalizumab (NTZ) is a high-efficacy therapy for relapsing-remitting multiple sclerosis (RRMS) that blocks peripheral immune cell migration into the central nervous…

Date: 2026-06-05

Family risk factors, dyadic coping, and family resilience in young stroke dyads: an actor-partner interdependence mediation model

Abstract: Stroke in young individuals constitutes a significant familial stressor, with ensuing family risk factors critically influencing recovery. While couples’ collaborative…

Date: 2026-06-05

Clinical features of anti-mGluR5 encephalitis and comparison according to MRI positivity: a systematic review and analysis

Abstract: Anti-metabotropic glutamate receptor 5 (mGluR5) encephalitis is a rare autoimmune neurological disorder with high clinical heterogeneity. The phenotypic spectrum of…

Date: 2026-06-05

Knowledge, attitudes, and practices toward chemotherapy resistance among oncologists: a multinational cross-sectional study

Abstract: This study assessed oncologists’ knowledge, attitudes, and practices regarding chemotherapy resistance across multiple countries. A cross-sectional study was conducted…

Date: 2026-06-05

Alexithymia of nursing students in higher vocational college: application of latent profile analysis and network analysis

Abstract: This study aims to identify different subgroups of alexithymia among vocational college nursing students, explore the critical values and core dimensions of these…

Date: 2026-06-05

Correlation between prognostic nutritional index and oral mucositis in patients with lung adenocarcinoma treated with almonertinib: a multicenter prospective study

Abstract: Oral mucositis (OM) is a common adverse reaction to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), and severe cases can impair patient…

Date: 2026-06-05

Identification and analysis of diagnostic senescence-related gene signatures for acute myocardial infarction based on multi-omics data and machine learning

Abstract: Acute myocardial infarction (AMI) incidence increases with population aging, alongside heightened cellular senescence; however, clinically useful senescence-related…

Date: 2026-06-05

Machine-learning prediction of impaired outcome in diabetic patients undergoing non-cardiac surgery

Abstract: Diabetic patients undergoing non-cardiac surgery are vulnerable to postoperative cardiovascular and cerebrovascular complications, yet risk stratification tools tailored…

Date: 2026-06-05

Combined associations of the frailty index and CHG index with cardiometabolic multimorbidity: a longitudinal study from the CHARLS cohort

Abstract: Frailty and metabolic dysfunction are major contributors to cardiometabolic multimorbidity (CMM). However, the joint influence of frailty and insulin resistance on the…

Date: 2026-06-05