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Maintenance oral viscous budesonide reduces dilation recurrence after esophageal atresia repair: a prospective clinical study

Abstract: Recurrent anastomotic stricture (AS) remains a major cause of morbidity after esophageal atresia (EA) repair. Although oral viscous budesonide (OVB) reduces dilation…

Date: 2026-05-14

Sex-related peripheral immune profile in ulcerative colitis: links to fatigue

Abstract: Ulcerative colitis (UC) is a chronic inflammatory disease marked by mucosal and systemic immune dysregulation. Fatigue is a common, burdensome extraintestinal symptom…

Date: 2026-05-14

Novel phenotypes of immune-mediated necrotizing myopathy identified independent of myositis-specific antibody specificity that improve prognostic stratification

Abstract: To systematically investigate the clinical characteristics and prognosis of patients with immune-mediated necrotizing myopathy (IMNM), and to explore the proteomic…

Date: 2026-05-14

CD36 aggravates ferroptosis in NK cells and dampens their anti-fibrotic activity in the liver

Abstract: Liver fibrosis is a major global health challenge, and it is an independent risk factor for the development of hepatocellular carcinoma (HCC). Several methods have been…

Date: 2026-05-14

Immunological research landscapes and emerging immune mechanisms in HIV/HBV co-infection: a bibliometric analysis (2014–2024)

Abstract: HIV and hepatitis B virus (HBV) co-infection remains a major global health challenge and is characterized by profound immune dysregulation, including chronic immune…

Date: 2026-05-14

Dynamic changes and clinical significance of the gut microbiota and serum metabolites in breast cancer onset, progression and chemotherapy intervention

Abstract: Alterations of the gut microbiota and host metabolic reprogramming are closely associated with the development of breast cancer and the treatment response; however,…

Date: 2026-05-14

Integrated CT-based assessment of muscle and adiposity for risk stratification in advanced pancreatobiliary cancer

Abstract: Pancreatobiliary cancers are highly aggressive, with limited prognostic markers in advanced stages. Cancer-associated malnutrition results in sarcopenia and adipose…

Date: 2026-05-14

Joint association of estimated skeletal muscle mass index and prognostic nutritional index with all-cause mortality in individuals with non-metastatic nasopharyngeal cancer

Abstract: The prognostic interplay between skeletal muscle mass and nutritional/immune status in non-metastatic nasopharyngeal carcinoma (NPC) is unclear. This study investigates…

Date: 2026-05-14

Integrating sarcopenia into ICU-acquired weakness risk stratification: a machine learning–based prediction model for critical care

Abstract: Sarcopenia is closely associated with weakness in elderly and various chronic disease populations. However, its specific role as a predisposing factor for ICU-acquired…

Date: 2026-05-14

Intermittent fasting alleviates irradiation-induced neuronal mitochondrial damage in mice

Abstract: Radiation-induced brain injury (RIBI) is a common side effect of cranial radiotherapy. Intermittent fasting (IF) decreases the risk of Brain aging disease by affecting…

Date: 2026-05-14