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High inappropriate red blood cell transfusion rate despite low overall use: a real-world multicenter study in 43 Spanish hospitals

Abstract: Since their implementation in Spain, adherence of hospitals to Patient Blood Management (PBM) programs has been variable, potentially influencing transfusion practices.…

Date: 2026-05-14

Cortical high-threshold and low-activation characteristics in adolescent depression: a cross-age differential analysis

Abstract: Adolescent depression exhibits distinct neurophysiological features, with marked age heterogeneity particularly in the resting motor threshold (RMT) measured during…

Date: 2026-05-14

Network structure of non-suicidal self-injury, alcohol and food addiction, and motivation in bus drivers

Abstract: Professional bus drivers work in a safety-critical, high-demand context that may increase vulnerability to non-suicidal self-injury (NSSI) and addictive behaviors.…

Date: 2026-05-14

Sexual minority (LGBQ+) women’s experiences of accessing addiction services: a qualitative study

Abstract: Lesbian, gay, bisexual, queer and other non-heterosexual (sexual minority) women experience significant health inequities in comparison with heterosexual women. Both…

Date: 2026-05-14

Research on refractive power calculation formula of intraocular lens based on the principle of double thick lens imaging

Abstract: This study aimed to develop and validate a novel formula for calculating intraocular lens (IOL) refractive power based on Gaussian optics and thick-lens imaging. This…

Date: 2026-05-14

Profiling dysregulated circRNA expression in diabetic retinopathy: elucidating putative mediators via a streptozotocin-induced mouse model

Abstract: Circular RNAs (circRNAs), a conserved class of non?coding RNAs, are hypothesized to play functional roles in diabetic retinopathy (DR), yet their expression landscape…

Date: 2026-05-14

Increased anti-nucleocapsid secretory IgA and consumption of complement component 3 in post-COVID syndrome patients

Abstract: Post-COVID syndrome represents a major global health challenge which is characterized by immune dysregulation, although many aspects of the immune response remain…

Date: 2026-05-14

Predicting poor response to anti-osteoporosis therapy: a machine learning model integrating clinical and novel biomarker data

Abstract: This study was conducted to develop and validate a prediction model integrating clinical characteristics and novel biomarkers. The goal was to identify patients at high…

Date: 2026-05-14

Predictive performance of cardiometabolic indices for prediabetes progression to diabetes and reversion to normoglycemia in adults: a cohort study

Abstract: To evaluate the associations of cardiometabolic indices with prediabetes progression and reversal and to identify noninvasive markers with relatively better…

Date: 2026-05-14

MAPRE2 is associated with macrophage-enriched innate immune dysregulation and malignant phenotypes in hepatocellular carcinoma

Abstract: Hepatocellular carcinoma (HCC) remains difficult to treat, and molecular determinants that link malignant behavior to the innate immune microenvironment are still…

Date: 2026-05-14