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Comparative study of the therapeutic effects of different medications on DM-associated dry eye syndrome after vitrectomy

Abstract: No prior studies have compared ciclosporin (CsA) and sodium hyaluronate (SH) eye drops for treating diabetes mellitus-associated dry eye syndrome (DMDES) after…

Date: 2026-05-12

LF3 exerts anti-osteosarcoma effects through Wnt signaling inhibition-coupled ferroptosis induction via HO-1/ACSL4 axis

Abstract: Osteosarcoma, the most common primary malignant bone tumor, predominantly affects adolescents and is characterized by high aggressiveness and early metastatic…

Date: 2026-05-12

Pediatric clinical nurses’ role conflict and adaptation status: time for improvement

Abstract: Pediatric nurses face unique clinical challenges that increase their risk of role conflict, which may adversely affect role adaptation and care quality. However, the…

Date: 2026-05-12

Association of the sarcopenia index with incident depressive symptoms and adverse depressive symptom trajectories

Abstract: The sarcopenia index (SI) is an accessible marker associated with muscle health, with cross-sectional link to depression has been reported. However, longitudinal…

Date: 2026-05-12

HDAC7 controls anti-viral and anti-tumor immunity by CD8 + T cells

Abstract: Class II histone deacetylases (HDAC) orchestrate T cell-dependent immune responses via the epigenetic control of genes and via the post-translational modification of…

Date: 2026-05-12

The long non-coding RNA CidecAS regulates hepatocyte lipid metabolism via the alpha-1 subunit of Na + /K + -ATPase

Abstract: The rising prevalence of metabolic-associated fatty liver disease (MAFLD) poses a serious public health threat, while long non-coding RNAs, key regulators of hepatic…

Date: 2026-05-12

Real-world comparison of anti-CD20 therapies: efficacy, infections, and immune profiles in a German cohort

Abstract: The use of anti-CD20 drugs has become a widespread therapeutic approach in systemic and central nervous system (CNS) neuroinflammation. Apart from the desired B-cell…

Date: 2026-05-12

Real-world efficacy and safety of Tenecteplase versus Alteplase in acute ischemic stroke: a propensity score-matched analysis

Abstract: Real-world evidence comparing Tenecteplase and Alteplase for acute ischemic stroke (AIS) remains limited. This study aimed to evaluate the comparative efficacy and…

Date: 2026-05-12

Efficacy and safety of efgartigimod as an add-on therapy in patients with NMOSD and MOGAD at the acute attack phase

Abstract: Neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein-associated disease (MOGAD) are autoimmune antibody-mediated diseases.…

Date: 2026-05-12

Stress accelerates hepatocellular carcinoma progression via a gut microbial-metabolite axis

Abstract: Hepatocellular carcinoma ranks among the most prevalent malignancies worldwide. While stress can modulate tumor initiation, progression, metastasis, and therapeutic…

Date: 2026-05-12