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Selective strategic adaptation and structural trade-offs in a public traditional Chinese medicine hospital under China's national performance appraisal: a longitudinal study

Abstract: Since 2019, China's National Performance Appraisal (NPA) has guided tertiary public hospitals from scale-oriented expansion toward high-quality development. While its…

Date: 2026-05-08

Panx1 and P2X7R are associated with impaired skeletal health and delayed bone development in early onset of type 1 diabetes

Abstract: Type 1 diabetes (T1D) is a chronic autoimmune endocrine disorder that disrupts multiple physiological systems beyond glucose homeostasis. An underrecognized complication…

Date: 2026-05-08

Clinical characteristics and risk factors of protein-losing enteropathy: a retrospective study

Abstract: Protein-losing enteropathy (PLE) is characterized by excessive gastrointestinal protein loss, yet systematic comparative studies across etiologies remain limited. This…

Date: 2026-05-08

Association between nutritional status at admission and inadequate bowel preparation in inflammatory bowel disease patients: a retrospective cohort study

Abstract: Malnutrition is highly prevalent among patients with inflammatory bowel disease (IBD). However, the relationship between nutritional status and the quality of bowel…

Date: 2026-05-08

Association of TyG and TyG/HDL with Helicobacter pylori infection status and urea breath test load: a cross-sectional study

Abstract: To evaluate the associations of the triglyceride–glucose index (TyG) and the TyG/high-density lipoprotein cholesterol ratio (TyG/HDL-C) with Helicobacter pylori…

Date: 2026-05-08

A novel auto-fluorescent porphyrin-lipid nanoparticle strategy for CTNNB1 gene silencing in hepatocellular carcinoma

Abstract: Hepatocellular carcinoma (HCC) remains a high-fatality cancer with limited effective therapies. CTNNB1 mutations, frequently observed in HCC, are associated with poor…

Date: 2026-05-08

Association between duration of dysphagia and dysphonia with insomnia: results from the National Health Interview Survey

Abstract: Insomnia markedly impairs health and quality of life. This study used the 2022 National Health Interview Survey (NHIS) data to explore the relationships among dysphagia…

Date: 2026-05-08

Associations of intracranial arterial stenosis and cerebral small vessel diseases with acute ischemic lesions in spontaneous intracerebral hemorrhage

Abstract: Cerebral small vessel disease (CSVD) has been declared to diffusion-weighted imaging (DWI) lesions in patients with intracerebral hemorrhage (ICH). The impact of large…

Date: 2026-05-08

The pathological Huntingtin CAG triplet expansion differentially affects the diagnosis of systemic and organ-specific autoimmune diseases

Abstract: In Huntington’s disease (HD), signs of inflammatory activation are found in the brain, cerebrospinal fluid, and blood. HD monocytes are reported to be hyperreactive in…

Date: 2026-05-08

Diagnostic accuracy of ultrasonography compared with nerve conduction studies in carpal tunnel syndrome

Abstract: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the upper extremity. Ultrasonography (USG) enables measurement of the median nerve…

Date: 2026-05-08