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Lymphocyte–to–high–density lipoprotein ratio is negatively associated with diabetic macular edema in type 2 diabetic patients

Abstract: Systemic immune-inflammatory imbalance plays a potential role in the development of diabetic macular edema (DME). The lymphocyte-to-high-density lipoprotein ratio (LHR)…

Date: 2026-05-01

Conversion from resistance to susceptibility: a dirty trick by PM 10

Abstract: The results of whole-body exposure to airborne particulate matter

Date: 2026-05-01

Local delivery of nerve growth factor in traumatic optic neuropathy: neuroprotective effects in a rat model

Abstract: In the present study, we established a rat model of optic nerve injury to evaluate whether direct local delivery of neurotrophic agents following traumatic optic…

Date: 2026-05-01

Prognostic factors and survival outcomes in patients undergoing limb-sparing surgery for primary malignant bone tumors

Abstract: Primary malignant bone tumors are aggressive neoplasms that frequently affect adolescents and young adults. Limb-sparing surgery (LSS) has become the preferred surgical…

Date: 2026-05-01

A radiology-based differential diagnostic model for pelvic chondrosarcoma using random forest algorithms

Abstract: To develop a non-invasive diagnostic method for pelvic chondrosarcoma using clinical and radiological features, aiming to improve early diagnostic accuracy and reduce…

Date: 2026-05-01

The anatomical bone corridor study of schanz screw placement in adolescent pelvic ring fractures via three-dimensional CT

Abstract: To define the anatomical boundaries of potential safe corridors for the placement of Schanz screws during external fixation of unstable pelvic fractures in normally…

Date: 2026-05-01

Subtype-dependent PD-L1 stability and immune context shape immunotherapy response in hepatocellular carcinoma

Abstract: Immune checkpoint inhibitors (ICIs) targeting the PD-1/PD-L1 axis have expanded treatment options for hepatocellular carcinoma (HCC), yet only a subset of patients…

Date: 2026-05-01

Direct-visualization endoscopic retrograde appendicitis therapy for chronic appendicitis with diarrhea: clinical features and outcomes

Abstract: Chronic appendicitis complicated with diarrhea presents diagnostic and therapeutic challenges due to its atypical and prolonged symptoms, often mimicking functional…

Date: 2026-05-01

Clinical efficacy, safety, and predictors of treatment response to SGLT2 versus DPP-4 inhibitors in type 2 diabetes: a retrospective comparative study

Abstract: The prevalence of type 2 diabetes is continuously increasing, and optimizing the treatment strategies for diabetes is an important clinical issue. SGLT2 inhibitors…

Date: 2026-05-01

CFD + CD14 + monocytes: potential pathogenic subset in myasthenia gravis uncovered by multi-omics integration and machine learning analysis

Abstract: Transcriptome?wide association study (TWAS) contributes to discovering novel susceptibility genes related to diseases. Single-cell RNA sequencing (scRNA-seq) has been…

Date: 2026-05-01