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Long-term radiographic outcomes following containment surgery for Legg–Calvé–Perthes disease in the reossification stage

Abstract: This study aimed to evaluate the long-term radiographic outcomes of containment surgery in children with Legg–Calvé–Perthes disease (LCPD) during the reossification…

Date: 2026-04-30

Impact of small area-level deprivation on survival outcomes in patients with Cholangiocarcinoma: a population-based multilevel survival analysis

Abstract: Cholangiocarcinoma (CCA) carries a dismal prognosis. Beyond clinical determinants, socioeconomic deprivation may also influence outcomes. Busan, a rapidly aging…

Date: 2026-04-30

A multicenter retrospective study: risk factors and nomogram construction for pathological escalation of gastric low-grade intraepithelial neoplasia

Abstract: Low-grade intraepithelial neoplasia (LGIN) is recognized as a precancerous lesion of gastric carcinoma. However, discrepancies have been observed between initial biopsy…

Date: 2026-04-30

Anti-A?3–10 monoclonal antibody 7B8 improves cognitive function and protects the blood-brain barrier in APP/PS1 mice by regulating the HMGB-1/RAGE/NF-?B pathway

Abstract: Alzheimer’s disease (AD), the most prevalent dementia, is primarily underpinned by the amyloid cascade hypothesis. Passive A? immunotherapy effectively reduces cerebral…

Date: 2026-04-30

Migraine with comorbid fibromyalgia: psychological burden and impact on frequency and severity of migraine attacks

Abstract: There is growing evidence suggesting a bidirectional relationship between fibromyalgia and migraine. The aim of this work was to study the impact of fibromyalgia on the…

Date: 2026-04-30

Clinical and serological characteristics of peripheral neuropathy in patients with primary Sjögren's syndrome

Abstract: To investigate the clinical features and serological characteristics of patients with primary Sjögren's syndrome (pSS) complicated with sensorimotor neuropathy (SMN),…

Date: 2026-04-30

Validation of LILR antibody specificities and development of LILRA3-specific antibodies

Abstract: Leukocyte immunoglobulin (Ig)-like receptors (LILRs) constitute a family of 11 structurally related receptors predominantly expressed on immune cells. Despite their…

Date: 2026-04-30

Zone-specific hepatocytes orchestrate the early onset of host immune defenses during Staphylococcus aureus bloodstream infection

Abstract: Bloodstream infections (BSI) are life-threatening conditions initiated by pathogens entering the circulation, with Staphylococcus aureus among the most lethal causative…

Date: 2026-04-30

Predictive value of peripheral blood eosinophil levels and dynamics for efficacy and safety of immune checkpoint inhibitors in non-small cell lung cancer: a real-world study

Abstract: Heterogeneous benefits from immunotherapy in advanced driver gene–negative non-small cell lung cancer (NSCLC) underscore the need for biomarkers predicting efficacy and…

Date: 2026-04-30

Oncology nutrition care in Indonesia: a cross-sectional survey to characterise practices, barriers and enablers among nutritionists and dietitians

Abstract: Nutrition care is essential for improving oncology treatment outcomes, however evidence on current practices and adherence to the Nutrition Care Process framework in…

Date: 2026-04-30