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Clinicopathological landscape and management trends of thyroid carcinoma over two decades: a single-institution study and risk stratification of central lymph node metastasis in T1 papillary thyroid carcinoma

Abstract: This study aimed to describe the clinicopathological landscape of thyroid disease, summarize long-term management trends of thyroid carcinoma (TC) and lymph node…

Date: 2026-04-30

Genomic alterations and dynamic molecular residual disease monitoring predict pathological response to neoadjuvant chemoimmunotherapy in esophageal squamous cell carcinoma

Abstract: Approximately 40-60% of patients with locally advanced esophageal squamous cell carcinoma (ESCC) exhibit suboptimal responses to neoadjuvant chemoimmunotherapy (NCIT),…

Date: 2026-04-30

Seasonal variations in hospital admissions and case-fatality of ischemic stroke: a nationwide analysis of >4.2 million cases in Germany

Abstract: Ischemic stroke is a leading cause of global morbidity and mortality, with seasonal variations potentially influencing both outcomes. While previous studies have…

Date: 2026-04-30

Impact of hypoglycemic regimens on cardiac recovery and quality of life after PCI in elderly AMI patients

Abstract: To investigate the impact of blood glucose control levels on cardiac function recovery and long-term prognosis in elderly patients with acute myocardial infarction (AMI)…

Date: 2026-04-30

Modulating CD38 enzymatic activity during antibody-based immunotherapy in multiple myeloma: a basic science perspective

Abstract: Multiple myeloma (MM) develops within a profoundly immunosuppressive bone marrow (BM) microenvironment. CD38, a multifunctional ectoenzyme highly expressed on malignant…

Date: 2026-04-29

Efficacy and safety analysis of autologous hematopoietic stem cell transplantation for extraocular retinoblastoma

Abstract: This study aimed to assess the efficacy and safety of autologous hematopoietic stem cell transplantation (Auto-HSCT) in pediatric patients with extraocular…

Date: 2026-04-29

Dysregulation of the immune microenvironment in essential thrombocythemia: the interplay of core genes and inflammation-related signaling pathways

Abstract: Essential thrombocythemia (ET) is a myeloproliferative disorder characterized as excessive platelet production. Early and accurate diagnosis is critical to manage the…

Date: 2026-04-29

Incidence, characteristics and suggestions for prevention of adverse events in supervised pediatric oncology exercise sessions

Abstract: Supervised exercise sessions in pediatric oncology offer numerous benefits, including mitigated treatment-related symptoms and improved physical and psychological…

Date: 2026-04-29

Hepatitis B vaccination in Chinese infants (2002-2006, Guangdong): long-term effectiveness in adulthood and biological features of HBV infection

Abstract: Hepatitis B virus infection is a serious health concern in China. The National Immunization Program has implemented universal hepatitis B vaccination for infants for…

Date: 2026-04-29

Sublingual methylcobalamin treatment in infants with prolonged jaundice due to vitamin B12 deficiency

Abstract: Ineffective erythropoiesis resulting from vitamin B12 deficiency leads to hemolysis. The breakdown of erythrocytes increases plasma bilirubin levels, which can cause…

Date: 2026-04-29