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Myeloid EGR1 contributes to Th17/Treg imbalance during acute liver allograft rejection in a rat model

Abstract: Ischemia-reperfusion injury (IRI) and acute rejection (AR) limit liver transplantation success. Early growth response 1 (EGR1) mediates stress and inflammation, yet its…

Date: 2026-09-21

ARID1A deficiency identifies molecular alterations and potential therapeutic implications in cervical clear cell carcinoma: an integrated genomic and clinicopathological study

Abstract: Cervical clear cell carcinoma (CCC) is a rare and aggressive subtype of cervical adenocarcinoma whose molecular drivers and therapeutic vulnerabilities remain…

Date: 2026-09-21

EV-derived miR-1246 promotes lymph node metastasis in esophageal squamous cell carcinoma through targeting the PPP2CB/NF-?B axis

Abstract: Lymph node metastasis (LNM) is a critical factor contributing to poor prognosis in esophageal squamous cell carcinoma (ESCC) patients. Consequently, elucidating its…

Date: 2026-09-21

Association of metabolic indices with in-stent restenosis and its angiographic severity after drug-eluting stent implantation: a case-control study

Abstract: Metabolic abnormalities may contribute to in-stent restenosis (ISR) after percutaneous coronary intervention, but the comparative associations of commonly used metabolic…

Date: 2026-09-21

Sex differences in amyloid transthyretin cardiomyopathy National Amyloidosis Centre staging at diagnosis: an analysis from a large single-center cohort

Abstract: Amyloid transthyretin cardiomyopathy (ATTR-CM) is a progressive infiltrative cardiomyopathy that has seen significant advances in diagnosis and treatment over the last…

Date: 2026-09-21

The identification value of common echocardiography parameters for improvement of mitral regurgitation after transcatheter aortic valve replacement in patients with aortic stenosis

Abstract: To analyze the factors influencing mitral regurgitation (MR) improvement in patients with aortic stenosis (AS) following transcatheter aortic valve replacement (TAVR),…

Date: 2026-09-21

Temporal and clinical heterogeneity of double M-protein multiple myeloma: diagnostic and treatment-emergent phenotypes

Abstract: Double M-protein multiple myeloma (DMP-MM) is an uncommon phenotype characterized by more than one detectable monoclonal component on serum protein electrophoresis…

Date: 2026-09-18

Dynamic white blood cell kinetics enable early risk stratification of differentiation syndrome in low- and intermediate-risk acute promyelocytic leukemia

Abstract: Differentiation syndrome (DS) is a potentially life-threatening complication during induction therapy for acute promyelocytic leukemia (APL). Previous studies have…

Date: 2026-09-18

Latent profile analysis of dietary behavior in pediatric patients with short stature: a single-center study in China

Abstract: To identify potential subtypes of dietary behavior in pediatric patients with short stature using latent profile analysis (LPA) and to explore the factors associated…

Date: 2026-09-18

A novel method based on ultrasound radiomics for predicting attainment of near-adult height in adolescents

Abstract: This study aimed to develop and validate a novel ultrasound radiomics model for predicting the attainment of near-adult height (NAH) in adolescents. This dual-center…

Date: 2026-09-18