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Predictive value of pre-existing thyroid autoantibodies for PD-1 inhibitor-induced hypothyroidism: a retrospective cohort study

Abstract: Immune checkpoint inhibitors (ICIs), particularly programmed cell death-1 (PD-1) inhibitors, have revolutionized cancer treatment but frequently induce thyroid…

Date: 2026-09-18

Glycemic burden-adjusted urinary glucose excretion deficit is associated with hyperuricemia in patients with type 2 diabetes

Abstract: To investigate the associations of glycemic burden-adjusted urinary glucose excretion deficit (GB-UGE deficit) with serum uric acid levels and prevalent hyperuricemia in…

Date: 2026-09-18

Procoagulant effects of extracellular vesicles in patients with livedo reticularis

Abstract: Extracellular vesicles (EVs) are lipid-delimited particles that mediate intercellular communication and have been implicated in both autoimmune and prothrombotic…

Date: 2026-09-18

Knowledge, attitudes, and practices regarding melasma among female patients

Abstract: Melasma is a common facial hyperpigmentation disorder with substantial psychosocial burden, yet patient-centered knowledge, attitudes, and practices (KAP) remain…

Date: 2026-09-18

Enrichment of the TRIM21-IgG complex in placental villi during HIV-1 infection

Abstract: Innate immunity constitutes a pivotal defense mechanism protecting the maternal-fetal interface against viral pathogens. However, the dynamics of placental immunity in…

Date: 2026-09-18

Molecular sensitization clusters in adult atopy: an ALEX 2 -based analysis from Eastern Europe

Abstract: Allergen sensitization profiles vary geographically, yet Eastern Europe data remain scarce. This study aimed to identify and characterize molecular sensitization…

Date: 2026-09-18

Cross-phenotype integration of eQTL-based Mendelian randomization and transcriptomics prioritizes BMP2K in IgA vasculitis with nephritis

Abstract: To prioritize candidate genes and compounds potentially associated with IgA vasculitis with nephritis (IgAVN) by integrating genetic and transcriptomic evidence across…

Date: 2026-09-18

Changes in gluten-free diet adherence and growth parameters among children with celiac disease during the COVID-19 pandemic

Abstract: Strict exclusion of gluten is the cornerstone of celiac disease (CD) management; nevertheless, maintaining dietary adherence remains challenging. The COVID-19 pandemic…

Date: 2026-09-18

Patient-reported symptom profiles in vitamin B 12 deficiency and pernicious anemia: a cross-sectional study using latent class analysis

Abstract: Pernicious anemia is a chronic autoimmune disease characterized by impaired of vitamin B 12 absorption and deficiency. Current diagnostic approaches rely on laboratory…

Date: 2026-09-18

Association between glycometabolic indicators and risk of early vascular aging and their predictive value

Abstract: Early vascular aging (EVA) elevates cardiovascular risk, and glycometabolic dysfunction is closely associated with arterial stiffness. Seven markers including TyG, CHG…

Date: 2026-09-18