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Association of pericoronary fat attenuation index and insulin resistance for the risk of cardiometabolic multimorbidity: a cross-sectional study

Abstract: Cardiometabolic multimorbidity (CMM) has become an increasingly serious public health problem. Patients with type 2 diabetes mellitus (T2DM) often present with multiple…

Date: 2026-04-21

Vitamin D dynamics predict treatment response to intravenous glucocorticoids in thyroid-associated ophthalmopathy: a retrospective cohort study

Abstract: Intravenous glucocorticoids (IVGC) represent first-line therapy for active moderate-to-severe thyroid-associated ophthalmopathy (TAO). The relationship between vitamin D…

Date: 2026-04-21

Endothelial and cardiac dysfunction in long COVID With cardiovascular symptoms is associated with imbalance in the ADMA–DDAH–NOx pathway

Abstract: Post-acute sequelae of COVID-19 (PASC) commonly feature lingering symptoms of persistent cardiovascular pathology, yet the mechanisms remain incompletely defined. The…

Date: 2026-04-21

Enhanced independent discriminative performance of elevated lipoprotein(a) for cardiovascular outcomes in patients with diabetes: a comparative analysis of optimal cutoff values

Abstract: This study aimed to evaluate the independent discriminative performance of elevated Lipoprotein(a) [Lp(a)] in identifying prevalent cardiovascular disease (CVD),…

Date: 2026-04-21

Effect of a nursing-based information–motivation–behavioral model on older patients with type 2 diabetes mellitus

Abstract: Older patients with type 2 diabetes mellitus (T2DM) frequently encounter challenges, including a diminished capacity for self-management, a high prevalence of negative…

Date: 2026-04-21

Development and validation of a diagnostic nomogram for Wagner grade?2 diabetic foot ulcers in hospitalized patients with type 2 diabetes

Abstract: Diabetic foot ulcers (DFUs) represent a severe and prevalent complication of diabetes, contributing to substantial disability and elevated mortality. This study aimed to…

Date: 2026-04-21

Identification and validation of a nomogram for psoriasis diagnosis: a novel biomarker combination with stable high expression in the early stage

Abstract: Psoriasis is a complex chronic inflammatory skin disease. While typical cases are often diagnosed based on clinical features, achieving objective assessment of disease…

Date: 2026-04-21

Interpretable two-stage deep learning for pediatric obstructive sleep apnea diagnosis using lateral cephalograms

Abstract: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a prevalent sleep-breathing disorder in pediatrics, yet early and accurate detection remains challenging due to the…

Date: 2026-04-21

Prognostic factors for cardiovascular-related mortality in pediatric hypertrophic cardiomyopathy: a retrospective cohort study with survival analysis and X-tile stratification

Abstract: To identify prognostic factors associated with cardiovascular-related mortality in children with hypertrophic cardiomyopathy (HCM) and to explore outcome-oriented risk…

Date: 2026-04-21

Development and internal validation of a multivariable risk stratification model for preoperative anxiety in surgical patients: a retrospective observational study

Abstract: Preoperative anxiety is common among surgical patients and is associated with adverse perioperative outcomes. Early identification of patients at elevated risk of…

Date: 2026-04-21