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Follicular fluid proteomic alterations associated with oocyte developmental potential in polycystic ovary syndrome

Abstract: PCOS is the most common disorder encompassing reproductive, metabolic, and endocrine abnormalities, and has an increased risk of adverse pregnancy and neonatal…

Date: 2026-04-16

Single-cell RNA sequencing of leukocytes at the maternal-fetal interface in physiological and pathological Nodal-deficient pregnancies

Abstract: Leukocytes at the maternal-fetal interface have critical functions during pregnancy in the prevention of maternal reactivity towards fetal alloantigens, suppression of…

Date: 2026-04-16

Assessment of ovarian reserve in girls diagnosed with pediatric cancer: a presentation of baseline data from a prospective follow-up study

Abstract: Overall survival for childhood cancer continues to improve, and with a large proportion of patients reaching reproductive age the question of fertility is becoming…

Date: 2026-04-16

Development and validation of a machine learning model for predicting postherpetic neuralgia risk

Abstract: Postherpetic neuralgia (PHN) is a debilitating complication of herpes zoster (HZ), and early identification of high-risk patients is crucial for timely intervention.…

Date: 2026-04-16

Identification and validation of druggable targets for cataract using mendelian randomization: functional insights from multi-omics and an oxidative stress model

Abstract: To identify druggable genes associated with cataract and investigate their functional roles under oxidative stress, thereby providing potential therapeutic targets.…

Date: 2026-04-16

Understanding perceptions of ophthalmology residents on pursuing a uveitis fellowship

Abstract: To investigate factors influencing the decision of ophthalmology residents in the United States to pursue a uveitis fellowship. A cross-sectional survey, with…

Date: 2026-04-16

Development and validation of a predictive nomogram for response to biologics and targeted therapy in Crohn’s disease: a retrospective cohort study

Abstract: Biologics and targeted therapies are a first-line treatment option for individuals with Crohn’s disease (CD). Nevertheless, clinical remission rates vary considerably…

Date: 2026-04-16

Stroke progression index as a dynamic metric is associated with functional outcome in progressive ischemic stroke with large vessel occlusion

Abstract: Current evaluation of progressive ischemic stroke (PIS) with large vessel occlusion (LVO) relies on static clinical or imaging measures and lacks quantitative assessment…

Date: 2026-04-16

Novel perspectives on the rare hemophagocytic lymphohistiocytosis: insights from a multi-center retrospective cohort

Abstract: Hemophagocytic syndrome, also known as hemophagocytic lymphohistiocytosis (HLH), is a rare clinical disease that is highly challenging to diagnose, has a low long-term…

Date: 2026-04-15

ANCA-associated vasculitis is associated with an increased risk of cardiac and vascular morbidity: results of a large-scale propensity-matched global retrospective cohort study

Abstract: Despite significantly improved therapies in recent years, long-term morbidity and mortality in ANCA-associated vasculitis (AAV) remain high. The leading causes of death…

Date: 2026-04-15