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Risk factors for central lymph node metastasis in papillary thyroid microcarcinoma: a simplified risk scoring system

Abstract: Central lymph node metastasis (CLNM) occurs in 20–50% of papillary thyroid microcarcinoma (PTMC) patients and influences surgical decision-making. Existing predictive…

Date: 2026-09-07

Predictive value of a preoperative computed tomography-derived perifracture soft-tissue envelope index for fracture-related infection after open reduction and internal fixation of tibial plateau fractures

Abstract: Fracture-related infection (FRI) is a major complication after open reduction and internal fixation (ORIF) of tibial plateau fractures. This study evaluated whether a…

Date: 2026-09-07

Serum phoenixin-14 levels in chronic kidney disease and hemodialysis patients: a cross-sectional study

Abstract: Phoenixin-14 (PNX-14) is a bioactive peptide associated with mitochondrial function, oxidative stress responses, and cellular protection. Although experimental data…

Date: 2026-09-07

First-line CDK4/6 inhibitor treatment of HR-positive, HER2-negative metastatic breast cancer: real-world data from Ho Chi Minh City Oncology Hospital, Vietnam

Abstract: This study aimed to characterize the tumor response rate, progression-free survival (PFS), and overall survival (OS) among patients with HR-positive, HER2-negative…

Date: 2026-09-07

Dual-region deep learning model integrating prostate and peri-prostatic adipose tissue MRI features for bone metastasis prediction in prostate cancer

Abstract: Bone metastasis (BM) is pivotal in prostate cancer (PCa) management. This study developed a multimodal model integrating MRI-derived deep features from the prostate…

Date: 2026-09-07

Premature ovarian insufficiency in patients with thyroid-related poly-autoimmunity

Abstract: An anticipated menopause is a disquieting health problem; its association with autoimmune disorders has been reported. However, data about the presence of premature…

Date: 2026-09-07

Node deposit size index as morphometric marker of intranodal tumour burden in node-positive oral cancer: a hypothesis-generating cohort study

Abstract: Cervical nodal metastasis critically influences prognosis in oral squamous cell carcinoma (OSCC), yet current staging does not quantify the degree of metastatic…

Date: 2026-09-07

Associations of exercise frequency, exercise session duration, and sleep duration with depressive symptoms among Chinese adolescents: a complex-survey cross-sectional analysis of CFPS2022

Abstract: Exercise and sleep are modifiable behaviors related to adolescent mental health, but the relevance of specific exercise-frequency categories, participant session…

Date: 2026-09-07

Associations between sodium intake and gut microbiota composition

Abstract: High salt intake is associated with adverse health outcomes. Emerging evidence highlights the importance of the gut microbiome in human health, but large-scale human…

Date: 2026-09-07

Ovarian cancer proteomic landscape changes across different pathological stages and biomarker-sets identified with integrative multiomics analysis

Abstract: Ovarian cancer (OV) is a highly lethal gynecological malignant tumor, with a high mortality, low survival rate, and lacking effective biomarkers. The concept of…

Date: 2026-09-07