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Prognostic significance of pretreatment peripheral blood inflammatory biomarkers in elderly patients with locally advanced cervical cancer undergoing definitive chemoradiotherapy

Abstract: Systemic inflammatory response plays a critical role in tumor progression and immune evasion. Elderly patients with locally advanced cervical squamous cell carcinoma…

Date: 2026-09-03

Arginine is a protective factor for risk and prognosis of gastric cancer: an observational and Mendelian randomization study

Abstract: Previous research has indicated that certain amino acids possess anti-tumor properties. However, the impact of blood amino acid levels on the risk of gastric cancer…

Date: 2026-09-03

APIM-guided dyadic nursing after colorectal cancer surgery: a propensity score-matched cohort study

Abstract: Recovery after colorectal cancer surgery is influenced not only by patient symptoms but also by caregiver capacity, psychological distress, self-efficacy, and dyadic…

Date: 2026-09-03

The ALP score: a novel composite index for prognostic risk stratification to chemo-immunotherapy in advanced non-small cell lung cancer

Abstract: This study aimed to investigate the value of a novel composite index, the ALP score (calculated as the product of lymphocyte count and serum albumin), in predicting the…

Date: 2026-09-03

Development and validation of a novel nomogram integrating visceral-to-subcutaneous fat ratio and neutrophil-percentage-to-albumin ratio for overall survival in locally advanced rectal cancer undergoing neoadjuvant radiotherapy

Abstract: Emerging evidence suggests that neutrophils are preferentially recruited to visceral adipose tissue, connecting adipose distribution to systemic inflammation. Visceral…

Date: 2026-09-03

Sex differences in the associations of multidomain risk factor profiles with incident major adverse cardiovascular events

Abstract: Major adverse cardiovascular events (MACE) exhibit sex-specific disparities, but comprehensive analyses of combined genetic and clinical risk factor profiles across…

Date: 2026-09-03

PVN-centered multi-omics and single-cell analyses suggest shared inflammatory and immune features in acute myocardial infarction-associated ventricular arrhythmia and atrial fibrillation

Abstract: Acute myocardial infarction (AMI) increases the risk of arrhythmias, particularly ventricular arrhythmias (VA), and atrial fibrillation (AF) is also common after AMI.…

Date: 2026-09-03

Systemic immune-inflammation index as a prognostic marker in heart failure with non-dialysis chronic kidney disease: a two-cohort derivation and validation study with head-to-head comparison against natriuretic peptides

Abstract: Heart failure (HF) and chronic kidney disease (CKD) frequently coexist and share chronic low-grade inflammation, oxidative stress, and thrombotic activation. Natriuretic…

Date: 2026-09-03

The impact of oral health literacy on oral health in lung cancer patients: the mediating role of psychosocial factors

Abstract: Lung cancer patients often have poor oral health due to treatment toxicities, increasing risks of oral mucositis, and pulmonary infection. Oral health literacy (OHL) is…

Date: 2026-09-03

Co-constructing stories with patients with heart failure to envision future remote care possibilities: a qualitative interview and sketching study

Abstract: Although remote patient management (RPM) shows promise for improving chronic heart failure (HF) management, its effectiveness depends on technology acceptance,…

Date: 2026-09-03