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Machine learning prediction of post-traumatic osteoarthritis based on three-dimensional printing-derived joint congruence biomechanics in ankle fractures

Abstract: Post-traumatic osteoarthritis (PTOA) develops in 20–40% of patients following ankle fracture fixation despite anatomic reduction. This study aimed to develop a machine…

Date: 2026-07-23

Combined oblique lateral interbody fusion and spinal endoscopy (Endo-OLIF) for degenerative lumbar disease: early clinical outcomes of a novel minimally invasive approach

Abstract: The combination of oblique lumbar interbody fusion (OLIF) and spinal endoscopy presents a promising minimally invasive approach for treating degenerative lumbar…

Date: 2026-07-23

Sex-related molecular phenotypes in anxiety-depressive disorders: a machine learning analysis of routine blood biomarkers

Abstract: Anxiety disorders and depressive disorders are the most prevalent mental disorders worldwide. Their diagnosis has long relied on clinical symptom assessment, and…

Date: 2026-07-23

Clinical study on the screening of biomarkers for Crohn’s disease based on blood metabolomics

Abstract: Crohn’s disease (CD) is a chronic inflammatory condition that affects the gastrointestinal tract. Currently, the diagnosis of CD is predominantly dependent on endoscopic…

Date: 2026-07-23

Efficacy and safety of tenofovir alafenamide in HBeAg-positive and negative chronic hepatitis B patients aged over 30 years with normal ALT and detectable HBV DNA: a 96-week retrospective two-center study

Abstract: The 2022 update of Chinese Guidelines for Chronic Hepatitis B (CHB) Management advocates initiating antiviral therapy regardless of alanine aminotransferase (ALT) status…

Date: 2026-07-23

A real-world assessment of healthcare resource utilization following IBS-Smart ® and Trio-Smart ® testing in patients with suspected irritable bowel syndrome

Abstract: IBS is a disorder of gut-brain interaction that is diagnosed positively but still requires a focused differential diagnosis and limited rule-out testing. IBS-Smart and…

Date: 2026-07-23

Predictive value of sarcopenia-related clinical indices for early disease progression in acute pancreatitis: a multicenter retrospective cohort study

Abstract: Early identification of patients at risk for severe Acute Pancreatitis (AP) remains a critical clinical challenge. Although sarcopenia reflects nutritional status and…

Date: 2026-07-23

Electroencephalography distinguished anti-N-methyl-D-aspartate receptor encephalitis and Creutzfeldt-Jakob disease

Abstract: Creutzfeldt-Jakob disease (CJD) and anti-NMDA receptor (anti-NMDAR) encephalitis are two diseases with different progression and prognosis, so it is crucial to…

Date: 2026-07-23

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR), atherogenic index of plasma and acute ischemic stroke classified by CISS

Abstract: Dyslipidemia is a significant contributor to ischemic stroke. The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and the…

Date: 2026-07-23

Neutrophil-to-albumin ratio as a predictor of sepsis-associated encephalopathy in patients with rheumatoid arthritis: an exploratory machine learning study

Abstract: Patients with rheumatoid arthritis (RA) face an elevated risk of sepsis and its associated neurological complications, most notably sepsis-associated encephalopathy…

Date: 2026-07-23