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Genetic landscape features associated with PD-L1 expression status in advanced lung adenocarcinoma: a targeted sequencing analysis

Abstract: The tumor immune microenvironment influences non-small cell lung cancer (NSCLC) progression and therapy response. Programmed death-ligand 1 (PD-L1) is a key biomarker…

Date: 2026-07-23

Real-world treatment patterns and outcomes of chemo-immunotherapy with or without radiotherapy in extensive-stage small cell lung cancer: the durvalumab expanded access cohort

Abstract: To describe real-world treatment patterns and outcomes among patients with extensive-stage small cell lung cancer (ES-SCLC) treated with first-line chemotherapy plus…

Date: 2026-07-23

Malnutrition predicts severe complications but not survival in laryngeal cancer surgery: a propensity-matched analysis

Abstract: The impact of preoperative malnutrition on clinical outcomes in patients undergoing laryngeal cancer surgery remains incompletely defined. This study aimed to evaluate…

Date: 2026-07-23

Acquired resistance to first-line immune checkpoint inhibitors in esophageal squamous cell carcinoma: progression patterns and prognostic implications

Abstract: Despite the survival benefit of first-line immune checkpoint inhibitor (ICI)-based therapy in advanced esophageal squamous cell carcinoma (ESCC), acquired resistance…

Date: 2026-07-23

Knowledge, attitudes, and practices regarding premature ventricular contractions among patients: a cross-sectional study

Abstract: This study aimed to investigate the knowledge, attitudes, and practices (KAP) regarding premature ventricular contractions (PVCs) among patients. A cross-sectional study…

Date: 2026-07-23

Is the Cally index truly a prognostic marker that predicts mortality in older patients with acute coronary syndrome?

Abstract: The C-reactive protein (CRP) -albumin- lymphocyte (CALLY) index has recently emerged as a promising prognostic marker, which reflecting inflammatory, nutrional and…

Date: 2026-07-23

Risk prediction for long-term cardiovascular events in patients with concurrent hypertension, HFpEF, and unstable angina: a multicenter machine learning-assisted cohort study

Abstract: Patients with concurrent hypertension, heart failure with preserved ejection fraction (HFpEF), and unstable angina pectoris (UAP) represent a high-risk population with…

Date: 2026-07-23

Mixed short-chain fatty acids and high-fiber diet reshape SCFA profiles and attenuate post-infarction cardiac fibrosis in mice

Abstract: Short-chain fatty acids (SCFAs) are microbiota-derived metabolites implicated in immunometabolic regulation. How their systemic and myocardial signatures diverge during…

Date: 2026-07-23

Higher remnant cholesterol to lymphocyte ratio is associated with vulnerable plaque features in acute coronary syndrome

Abstract: Remnant cholesterol to lymphocyte ratio (RCLR) integrates atherogenic lipid metabolism and systemic inflammation, potentially reflecting plaque vulnerability in acute…

Date: 2026-07-23

Febrile neutropenia in children and adolescents with acute myeloid leukemia during induction therapy

Abstract: Febrile neutropenia (FN) is a serious and potentially life-threatening complication in children with acute myeloid leukemia (AML), particularly during induction…

Date: 2026-07-22