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Avatrombopag switching from other thrombopoietic agents in severe and persistent cancer treatment-induced thrombocytopenia: a multicentre real-world study

Abstract: Severe and persistent cancer treatment-induced thrombocytopenia (CTIT) remains a major obstacle to continuation of antineoplastic therapy and faces an increased risk of…

Date: 2026-07-22

Efficacy and safety of intrathyroidal dexamethasone therapy in severe subacute thyroiditis – a real-world prospective single center study

Abstract: Clinically severe subacute thyroiditis (SAT) requires high cumulative doses of systemic steroids. The aim of the DLISAT study was to assess efficacy and safety of…

Date: 2026-07-22

Thyroid follicular cell-derived GDF15 attenuates inflammation and lipid dysregulation in Hashimoto's thyroiditis

Abstract: Hashimoto's thyroiditis (HT) is a prevalent autoimmune thyroid disorder, typically triggers localized thyroid inflammation and systemic dyslipidemia, and progression to…

Date: 2026-07-22

Association between inflammatory indicators derived from preconception complete blood count and specific adverse fetal, neonatal, and pregnancy outcomes: a national cohort study

Abstract: Adverse fetal and neonatal outcomes, including small for gestational age (SGA), large for gestational age (LGA), and low birth weight (LBW), seriously endanger maternal…

Date: 2026-07-22

Associations of dietary quality and physical activity with glycemic control in patients with type 2 diabetes: the moderating role of trait mindfulness

Abstract: Dietary quality and physical activity are fundamental components of glycemic management in patients with type 2 diabetes mellitus (T2DM). However, glycemic responses to…

Date: 2026-07-22

Association of continuous glucose monitoring metrics with early diabetic kidney disease in early-onset type 2 diabetes

Abstract: The rising prevalence of early-onset type 2 diabetes (T2DM) has become a major public health concern, with these patients facing a particularly high risk of early…

Date: 2026-07-22

Serum 25(OH)D3 and advanced liver fibrosis in type 2 diabetes: a Chinese hospital cohort with NHANES validation and mortality follow-up

Abstract: Liver fibrosis is an important predictor of mortality in patients with type 2 diabetes mellitus (T2DM). Current clinical practice relies on total 25-hydroxyvitamin D,…

Date: 2026-07-22

Altered body composition in children and adolescents with achondroplasia

Abstract: Achondroplasia is characterized by disproportionate short stature, yet little is known about how growth patterns and body composition differ from peers during childhood…

Date: 2026-07-22

Muscle mass and function in patients with type 2 diabetes mellitus: a characteristic analysis based on sex, age, and BMI

Abstract: To investigate the characteristics and determinants of muscle mass and muscle function in patients with type 2 diabetes mellitus (T2DM), stratified by sex, age, and body…

Date: 2026-07-22

Art an 3 as a candidate recombinant antigen for Artemisia pollen immunotherapy: comparative efficacy and mechanistic insights

Abstract: Artemisia pollen is a major cause of seasonal respiratory allergy, yet allergen-specific immunotherapy (AIT) still relies mainly on crude extracts. Art an 3 is a major…

Date: 2026-07-22