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CCR1-mediated monocyte chemotaxis in the immunopathology of primary Sjögren’s syndrome: multi-omics integration analysis and computational target prioritization implicating Polygonatum odoratum

Abstract: Primary Sjögren’s syndrome (pSS) is a chronic systemic autoimmune disease with no specific etiological treatment. Polygonatum odoratum , a traditional yin-nourishing…

Date: 2026-07-20

Treatment patterns and survival outcomes in elderly patients with intrahepatic cholangiocarcinoma: NCDB analysis

Abstract: Intrahepatic cholangiocarcinoma (ICC) is a rare malignancy with a poor prognosis and rising incidence that is most commonly diagnosed in older adults. However, elderly…

Date: 2026-07-20

Predicting patient-specific quality assurance outcomes in helical tomotherapy using plan complexity and 3D dose-distribution radiomics

Abstract: Pretreatment patient-specific quality assurance (PSQA) for helical tomotherapy (HT) is time-consuming and resource-intensive. Machine-learning-based screening tools may…

Date: 2026-07-20

Treatment patterns and outcomes of patients with a diagnosis of metastatic pancreatic adenocarcinoma in the United States, 2019–2024

Abstract: Approximately half of patients with pancreatic cancer present with metastatic disease at diagnosis, for whom 5?year survival remains ~3%. This retrospective study…

Date: 2026-07-20

Stereotactic versus hippocampal avoidance whole-brain radiotherapy combined with immune checkpoint inhibitors for multiple brain metastases in non-small cell lung cancer: a multi-center retrospective study

Abstract: The optimal radiotherapy (RT) approach combined with immune checkpoint inhibitors (ICIs) for non-small cell lung cancer (NSCLC) patients with multiple brain metastases…

Date: 2026-07-20

Foundation model-enhanced multimodal radiomics for predicting response to chemo-immunotherapy in advanced lung squamous cell carcinoma

Abstract: To develop and validate a foundation model–driven multimodal fusion framework for non-invasive prediction of treatment response to first-line chemo-immunotherapy in…

Date: 2026-07-20

Impact of multi-channel follow-up as continuous nursing on cancer pain control, adverse reactions, and quality of life in patients with digestive tract tumors: a controlled study of 136 cases

Abstract: This study was designed to assess the effectiveness of multi-channel follow-up as a continuous nursing intervention in monitoring pain relief, adverse effects and…

Date: 2026-07-20

Outcomes of infantile leukemia in a Saudi multicenter cohort: patterns of treatment response, treatment failure, relapse, and survival

Abstract: Infantile leukemia is a rare and aggressive form of pediatric leukemia associated with high rates of treatment failure, relapse, and mortality. Despite advances in…

Date: 2026-07-20

Association of uric acid, HDL-C, and homocysteine with coronary artery disease and stenosis

Abstract: Coronary heart disease (CHD) remains a major global cause of morbidity and mortality. Identifying reliable and non-invasive biochemical markers that reflect CHD severity…

Date: 2026-07-20

CHA 2 DS 2 -VA and non-CHA 2 DS 2 -VA components as predictors of mortality after cavotricuspid isthmus ablation: a clinical tool for long-term risk stratification

Abstract: Typical atrial flutter (AFL) is associated with considerable morbidity and mortality despite high procedural success rates of cavotricuspid isthmus (CTI) ablation. While…

Date: 2026-07-20