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Long-term outcomes of definitive chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil for postoperative locoregional recurrent esophageal cancer: a prospective phase II study

Abstract: Postoperative locoregional recurrence of esophageal cancer remains a major clinical challenge, with no established standard salvage treatment. Although definitive…

Date: 2026-07-09

Mechanisms of drowning in children: influence of cold shock response on repolarization patterns and arrhythmia burden in healthy children

Abstract: While drowning plays a particularly important role in children, the data on the physiology of drowning in this population are scarce. Both the cold shock response and…

Date: 2026-07-09

Association between neutrophil percentage-to-albumin ratio and adverse clinical outcomes after successful percutaneous coronary intervention for chronic total occlusion: a cohort study

Abstract: Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has improved outcomes, yet residual cardiovascular risk persists. The neutrophil…

Date: 2026-07-09

Single-point insulin sensitivity estimator and left main and/or three-vessel disease in patients aged 45 years or older with acute coronary syndrome: findings from the CCC-ACS project

Abstract: Severe coronary anatomical involvement is clinically important in patients with acute coronary syndrome (ACS), yet evidence on its relationship with insulin sensitivity…

Date: 2026-07-09

Thyroid feedback quantile-based index predicts 90-day all-cause mortality or readmission in hospitalized heart failure patients: a retrospective cohort study

Abstract: The Thyroid Feedback Quantile-Based Index (TFQI), a recently developed indicator derived from thyroid stimulating hormone (TSH) and free thyroxine (FT4) levels, has…

Date: 2026-07-09

Comparative analysis of myocardial strain parameters in acute decompensated heart failure phenotypes: a cross-sectional study

Abstract: To investigate the differences in two-dimensional speckle tracking echocardiography (2D-STE) parameters among patients with different types of acute decompensated heart…

Date: 2026-07-09

The associations of the triglyceride–glucose index and estimated glucose disposal rate with incident cardiometabolic multimorbidity vary across obesity phenotypes: a longitudinal cohort study

Abstract: Cardiometabolic multimorbidity (CMM) is increasingly common in older adults and is closely linked to insulin resistance (IR). However, whether IR surrogates perform…

Date: 2026-07-09

Development and validation of an interpretable machine learning model for venous thromboembolism risk prediction in patients with lung cancer: a real-world study

Abstract: Venous thromboembolism (VTE) is a common complication in patients with lung cancer and remains difficult to predict accurately using existing risk assessment tools. This…

Date: 2026-07-08

SkinDet-YOLO: a context- and boundary-aware yolov8-based framework for skin disease detection

Abstract: Skin diseases are among the most common human disorders, and accurate localization of suspicious lesions in clinical or dermoscopic images is a critical first step…

Date: 2026-07-08

The double-edged sword of generative AI in dermatology: a multi-component cross-sectional study on physician burnout, patient satisfaction, and communication quality

Abstract: Generative artificial intelligence (GenAI), particularly large language models (LLMs), is rapidly integrating into clinical settings. However, its net effect on…

Date: 2026-07-08